HELPER T CELL

IPA (US):

 Dictionary entry overview: What does helper T cell mean? 

• HELPER T CELL (noun)
  The noun HELPER T CELL has 1 sense:

1. T cell with CD4 receptor that recognizes antigens on the surface of a virus-infected cell and secretes lymphokines that stimulate B cells and killer T cells; helper T cells are infected and killed by the AIDS virus

  Familiarity information: HELPER T CELL used as a noun is very rare.

 Dictionary entry details 

• HELPER T CELL (noun)

Sense 1

Meaning:

T cell with CD4 receptor that recognizes antigens on the surface of a virus-infected cell and secretes lymphokines that stimulate B cells and killer T cells; helper T cells are infected and killed by the AIDS virus

Classified under:

Nouns denoting body parts

Synonyms:

CD4 cell; CD4 T cell; helper cell; helper T cell

Hypernyms ("helper T cell" is a kind of...):

T cell; T lymphocyte (a small lymphocyte developed in the thymus; it orchestrates the immune system's response to infected or malignant cells)

 Context examples 

IL-12 and IL-18 are involved in helper T cell differentiation.

(Cytokine Network Pathway, NCI Thesaurus/BIOCARTA)

Cytotoxic T cell activation also requires newitional signals provided by helper T cells in newition to signals provided by antigen-presenting cells.

(Cytotoxic T Cell Surface Pathway, NCI Thesaurus/BIOCARTA)

HIV infection is associated with immunosuppression caused by a dramatic reduction in the helper T cell population.

(HIV Induced T Cell Apoptosis Pathway, NCI Thesaurus/BIOCARTA)

GPI-0100 containing vaccines have been used with both viral and tumor antigens to elicit a Type 1 helper T cell response for those diseases in which a cytotoxic T lymphocyte (CTL) response is desired.

(GPI-0100, NCI Thesaurus)

A helper T cell is a type of white blood cell and a type of lymphocyte.

(helper T cell, NCI Dictionary)

Once this cell encounters an antigen in the presence of helper T cells and becomes activated, it moves to the next stage of B-lymphocyte development.

(Naive Pregerminal Center B-Lymphocyte, NCI Thesaurus)

The synthetic peptide PADRE is a universal helper T cell epitope.

(PADRE-CMV Fusion Peptide Vaccine, NCI Thesaurus)

The event of providing fragments of foreign proteins, including viruses and bacteria, to the helper T cells.

(Antigen Presentation, NCI Thesaurus)

IL-13, a cytokine mainly secreted by type 2 helper T cells, plays a key role in the induction of allergic inflammation.

(Lebrikizumab, NCI Thesaurus)

A vaccine composed of tumor-associated antigen, mutant K-ras, which produces both a cytotoxic and helper T cell response to challenge tumor cells expressing the relevant K-ras oncogene.

(K-RAS Protein Vaccine, NCI Thesaurus)