GROWTH FACTOR

Pronunciation (US):

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 Dictionary entry overview: What does growth factor mean? 

• GROWTH FACTOR (noun)
  The noun GROWTH FACTOR has 1 sense:

1. a protein that is involved in cell differentiation and growth

  Familiarity information: GROWTH FACTOR used as a noun is very rare.

 Dictionary entry details 

• GROWTH FACTOR (noun)

Sense 1

Meaning:

A protein that is involved in cell differentiation and growth

Classified under:

Nouns denoting substances

Hypernyms ("growth factor" is a kind of...):

protein (any of a large group of nitrogenous organic compounds that are essential constituents of living cells; consist of polymers of amino acids; essential in the diet of animals for growth and for repair of tissues; can be obtained from meat and eggs and milk and legumes)

Hyponyms (each of the following is a kind of "growth factor"):

nerve growth factor; NGF (a protein that is involved in the growth of peripheral nerve cells)

 Context examples 

It is used in patients with certain mutations (changes) in a cell protein called epidermal growth factor receptor (EGFR).

(Afatinib dimaleate, NCI Dictionary)

This allele, which encodes RAC-alpha serine/threonine-protein kinase protein, plays a role in mediating the effects of various growth factors and is involved in the transduction of anti-apoptotic and proliferation signals in T-cells.

(AKT1 wt Allele, NCI Thesaurus)

HER-2, a tyrosine kinase receptor for epidermal growth factor (EGF) (also known as neu and ErbB2), is overexpressed by some breast, ovarian, and gastric cancers.

(Adenovirus HER2-Transduced Autologous Dendritic Cell Vaccine, NCI Thesaurus)

Her-2/neu, a tumor-associated antigen and member of the epidermal growth factor receptor (EGFR) family of tyrosine kinases, is overexpressed in various tumor cell types.

(Adenovirus Encoding Rat HER-2/neu, NCI Thesaurus)

Flt3L is a hematopoietic growth factor and ligand for the Flt3 tyrosine kinase receptor.

(Ad-hCMV-Flt3L, NCI Thesaurus)

Amphiregulin is a heparin-binding, heparin-inhibited member of the epidermal growth factor family and an autocrine growth factor for human keratinocytes.

(Amphiregulin, NCI Thesaurus)

Blockade of IL-1 activity may inhibit the cascade of downstream pro-angiogenic factors such as vascular endothelial cell growth factor, tumor necrosis factor-alpha, and IL-6, resulting in inhibition of tumor angiogenesis.

(Anakinra, NCI Thesaurus)

The silibinin component of milk thistle has been shown to inhibit growth factor receptor-mediated mitogenic and cell survival signaling, thereby inhibiting tumor growth.

(Milk thistle, NCI Thesaurus)

A recombinant fusion protein derived from the coding sequences of two growth factors, interleukin-3 (IL-3) and granulocyte-macrophage colony-stimulating factor (GM-CSF).

(Milodistim, NCI Thesaurus)

This allele, which encodes hepatocyte growth factor receptor protein, plays a role in the regulation of cellular tyrosine-kinase activity.

(MET wt Allele, NCI Thesaurus)