GLUTATHIONE PEROXIDASE

Pronunciation (US):

(GB):

 Dictionary entry overview: What does glutathione peroxidase mean? 

• GLUTATHIONE PEROXIDASE (noun)
  The noun GLUTATHIONE PEROXIDASE has 1 sense:

1. an enzyme in the body that is a powerful scavenger of free radicals

  Familiarity information: GLUTATHIONE PEROXIDASE used as a noun is very rare.

 Dictionary entry details 

• GLUTATHIONE PEROXIDASE (noun)

Sense 1

Meaning:

An enzyme in the body that is a powerful scavenger of free radicals

Classified under:

Nouns denoting substances

Hypernyms ("glutathione peroxidase" is a kind of...):

antioxidant (substance that inhibits oxidation or inhibits reactions promoted by oxygen or peroxides)

peroxidase (any of a group of enzymes (occurring especially in plant cells) that catalyze the oxidation of a compound by a peroxide)

 Context examples 

Ebselen acts as a glutathione peroxidase mimetic and is thereby able to prevent cellular damage induced by reactive oxygen species (ROS).

(Ebselen, NCI Thesaurus)

Hexylresorcinol may also inhibit oxidative DNA damage by enhancing the activity of antioxidant enzymes, including glutathione peroxidase and glutathione reductase, which facilitate scavenging reactive oxygen molecules by glutathione (GSH).

(Hexylresorcinol, NCI Thesaurus)

Glutathione peroxidase 1 (203 aa, ~22 kDa) is encoded by the human GPX1 gene.

(Glutathione Peroxidase 1, NCI Thesaurus)

Glutathione peroxidase 2 (190 aa, ~22 kDa) is encoded by the human GPX2 gene.

(Glutathione Peroxidase 2, NCI Thesaurus)

Glutathione is also important as a cofactor for the enzyme glutathione peroxidase, in the uptake of amino acids, and in the synthesis of leukotrienes.

(Glutathione, NCI Thesaurus)

Glutathione peroxidase (GPx), for example, removes peroxides using glutathione as a reducing agent, and glutathione reductase (GSR) regenerates reduced glutathione.

(Free Radical Induced Apoptosis Pathway, NCI Thesaurus/BIOCARTA)

This agent also modulates the activity of hepatic enzymes such as alanine aminotransferase (ALT), aspartate aminotransferase (AST), superoxide dismutase (SOD) and glutathione peroxidase.

(Magnesium Isoglycyrrhizinate, NCI Thesaurus)

This agent acts as an antioxidant when incorporated into glutathione peroxidase and has been shown to exhibit potent chemopreventive activity in animal models.

(Methylselenocysteine, NCI Thesaurus)

As a trace mineral that is toxic in high doses, selenium is a cofactor for glutathione peroxidase, an anti-oxidant enzyme that neutralizes hydrogen peroxide.

(L-Selenomethionine, NCI Thesaurus)

This allele, which encodes glutathione peroxidase 2 protein, plays a role in digestion and detoxification.

(GPX2 wt Allele, NCI Thesaurus)