English Dictionary |
GLOBIN
Pronunciation (US): | (GB): |
Dictionary entry overview: What does globin mean?
• GLOBIN (noun)
The noun GLOBIN has 1 sense:
1. a colorless protein obtained by removing heme from hemoglobin; the oxygen carrying compound in red blood cells
Familiarity information: GLOBIN used as a noun is very rare.
Dictionary entry details
Sense 1
Meaning:
A colorless protein obtained by removing heme from hemoglobin; the oxygen carrying compound in red blood cells
Classified under:
Nouns denoting substances
Synonyms:
globin; haematohiston; hematohiston
Hypernyms ("globin" is a kind of...):
simple protein (a protein that yields only amino acids when hydrolyzed)
Holonyms ("globin" is a substance of...):
haemoglobin; Hb; hemoglobin (a hemoprotein composed of globin and heme that gives red blood cells their characteristic color; function primarily to transport oxygen from the lungs to the body tissues)
Context examples
A form of alpha thalassemia that results from reduced protein production from three of the four alpha-globin genes.
(Hemoglobin H Disease, NCI Thesaurus)
A condition in which a person is heterozygous for a globin gene, with a one normal allele and one defective allele.
(Hemoglobin Trait, NCI Thesaurus)
An inherited disorder characterized by structural alterations of a globin chain within the hemoglobin molecule.
(Hemoglobinopathy, NCI Thesaurus)
A state in which both beta-globin alleles code for a C or E variant but which leads to such minor changes to the hemoglobin that it does not cause disease.
(Homozygous Hemoglobin C or E, Non-Disease, NCI Thesaurus)
A genetic hematologic disorder characterized by partial or complete absence of the alpha globin chains of the heme molecule.
(Alpha Thalassemia, NCI Thesaurus)
A severe and rare form of alpha thalassemia characterized by the absence of alpha globin chains.
(Hemobglobin Bart's Hydrops, NCI Thesaurus)
A condition in which a person has reduced protein production from two of the four alpha-globin alleles.
(Alpha Thalassemia Trait, NCI Thesaurus)
A condition in which a person has reduced protein production from one of the four alpha-globin alleles.
(Alpha Thalassemia Silent Carrier, NCI Thesaurus)
Alpha-globin transcription factor CP2 (502 aa, ~57 kDa) is encoded by the human TFCP2 gene.
(Alpha-Globin Transcription Factor CP2, NCI Thesaurus)
A heterozygous state in which a person has a mutation in a beta globin allele causing beta thalassemia, together with other structural variants in the other allele.
(Beta Thalassemia Plus Structural Variants, NCI Thesaurus)
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