GLIOBLASTOMA

Pronunciation (US):

(GB):

 Dictionary entry overview: What does glioblastoma mean? 

• GLIOBLASTOMA (noun)
  The noun GLIOBLASTOMA has 1 sense:

1. a fast-growing malignant brain tumor composed of spongioblasts; nearly always fatal

  Familiarity information: GLIOBLASTOMA used as a noun is very rare.

 Dictionary entry details 

• GLIOBLASTOMA (noun)

Sense 1

Meaning:

A fast-growing malignant brain tumor composed of spongioblasts; nearly always fatal

Classified under:

Nouns denoting stable states of affairs

Synonyms:

glioblastoma; spongioblastoma

Hypernyms ("glioblastoma" is a kind of...):

brain tumor; brain tumour (a tumor in the brain)

 Context examples 

A synthetic peptide sequence derived from the tumor specific mutant variant of epidermal growth factor receptor EGFRvIII originally found in glioblastoma multiforme, caused by the deletion of exons 2-7.

(EGFRvIII Peptide, NCI Thesaurus)

These lesions typically affect young adults and have an intrinsic tendency for malignant progression to anaplastic astrocytoma and, ultimately, glioblastoma.

(Diffuse Astrocytoma, NCI Thesaurus/Adapted from WHO)

Also called glioblastoma, glioblastoma multiforme, and grade IV astrocytoma.

(GBM, NCI Dictionary)

A general term for tumors of the central nervous system, including astrocytomas, ependymal tumors, glioblastoma multiforme, and primitive neuroectodermal tumors.

(Glial tumor, NCI Dictionary)

Glioblastoma usually occurs in adults and affects the brain more often than the spinal cord.

(Glioblastoma, NCI Dictionary)

A molecular subtype of glioblastoma characterized by lack of p53 mutations, chromosome 7 amplifications or deletions, and high levels of EGFR amplification.

(Classical Glioblastoma, NCI Thesaurus)

This agent also inhibits growth and induces apoptosis of glioblastoma cells via a mechanism independent of estrogen receptor-related mechanisms.

(CC-8490, NCI Thesaurus)

Some glioblastomas express the gene at reduced levels.

(BAI1 wt Allele, NCI Thesaurus)

Boron neutron capture therapy is being studied as a treatment for glioblastoma multiforme and recurrent head and neck cancer.

(Boron neutron capture therapy, NCI Dictionary)

The brainstem glioma/glioblastoma is more common.

(Brain Stem Ependymoma, NCI Thesaurus)