FLUOXETINE

Pronunciation (US):

(GB):

 Dictionary entry overview: What does fluoxetine mean? 

• FLUOXETINE (noun)
  The noun FLUOXETINE has 1 sense:

1. a selective-serotonin reuptake inhibitor commonly prescribed as an antidepressant (trade names Prozac or Sarafem); it is thought to work by increasing the activity of serotonin in the brain

  Familiarity information: FLUOXETINE used as a noun is very rare.

 Dictionary entry details 

• FLUOXETINE (noun)

Sense 1

Meaning:

A selective-serotonin reuptake inhibitor commonly prescribed as an antidepressant (trade names Prozac or Sarafem); it is thought to work by increasing the activity of serotonin in the brain

Classified under:

Nouns denoting man-made objects

Synonyms:

fluoxetine; fluoxetine hydrocholoride; Prozac; Sarafem

Hypernyms ("fluoxetine" is a kind of...):

selective-serotonin reuptake inhibitor; SSRI (an antidepressant drug that acts by blocking the reuptake of serotonin so that more serotonin is available to act on receptors in the brain)

 Context examples 

The hydrochloride salt of duloxetine, a fluoxetine derivative belonging to the class of selective serotonin (5-HT) and norepinephrine (NE) reuptake inhibitors (SSNRIs) and exhibiting antidepressant activity.

(Duloxetine hydrochloride, NCI Thesaurus)

Fluoxetine binds to the presynaptic serotonin receptor resulting in negative allosteric modulation of the receptor complex, thereby blocking recycling of serotonin by the presynaptic receptor.

(Fluoxetine Hydrochloride, NCI Thesaurus)

The hydrochloride salt form of fluoxetine, a diphenhydramine derivative and selective serotonin reuptake inhibitor with antidepressant, antiobsessional and antibulimic effects.

(Fluoxetine Hydrochloride, NCI Thesaurus)

Inhibition of serotonin reuptake by fluoxetine enhances serotonergic function through serotonin accumulation in the synaptic space, resulting in long-term desensitization and downregulation of 5HT1 (serotonin) receptors leading to antidepressant, antiobsessional and antibulimic effects via various nerve pathways in the brain.

(Fluoxetine Hydrochloride, NCI Thesaurus)