English Dictionary |
FILAGGRIN
Pronunciation (US): | (GB): |
Dictionary entry overview: What does filaggrin mean?
• FILAGGRIN (noun)
The noun FILAGGRIN has 1 sense:
1. the main protein of the keratohyalin granules
Familiarity information: FILAGGRIN used as a noun is very rare.
Dictionary entry details
Sense 1
Meaning:
The main protein of the keratohyalin granules
Classified under:
Nouns denoting substances
Context example:
the specific target of the immune response in rheumatoid arthritis is filaggrin
Hypernyms ("filaggrin" is a kind of...):
protein (any of a large group of nitrogenous organic compounds that are essential constituents of living cells; consist of polymers of amino acids; essential in the diet of animals for growth and for repair of tissues; can be obtained from meat and eggs and milk and legumes)
Context examples
This allele, which encodes filaggrin protein, plays a role in promoting disulfide-bond formation in intermediate filaments.
(FLG wt Allele, NCI Thesaurus)
Filaggrin (4061 aa, ~435 kDa) is encoded by the human FLG gene.
(Filaggrin, NCI Thesaurus)
Azelaic acid exerts its keratolytic and comedolytic effects by reducing the thickness of the stratum corneum and decreasing the number of keratohyalin granules by reducing the amount and distribution of filaggrin in epidermal layers.
(Azelaic Acid, NCI Thesaurus)
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