FIBROBLAST

Pronunciation (US):

(GB):

 Dictionary entry overview: What does fibroblast mean? 

• FIBROBLAST (noun)
  The noun FIBROBLAST has 1 sense:

1. a cell from which connective tissue develops

  Familiarity information: FIBROBLAST used as a noun is very rare.

 Dictionary entry details 

• FIBROBLAST (noun)

Sense 1

Meaning:

A cell from which connective tissue develops

Classified under:

Nouns denoting body parts

Hypernyms ("fibroblast" is a kind of...):

embryonic cell; formative cell (a cell of an embryo)

 Context examples 

They are relatively undifferentiated and may become fibroblasts, macrophages, or smooth muscle cells.

(Murine Pericytes, NLM, Medical Subject Headings)

A spindle-shaped cell that exhibits characteristics of both fibroblasts and smooth muscle cells.

(Myofibroblast, NCI Thesaurus)

It has neurotrophic activities and is mitogenic to certain, but not to all, fibroblast cell lines.

(Neurite Growth-Promoting Factor 2, NCI Thesaurus)

It is composed of perineurial-like fibroblasts and Schwann cells.

(Neurofibroma, NCI Thesaurus)

A murine monoclonal antibody (MoAb) against human fibroblast activation protein (FAP).

(Monoclonal Antibody F19, NCI Thesaurus)

A purine derivative with antineoplastic and anti-angiogenic properties. 6-methylmercaptopurine riboside (6-MMPR) inhibits amidophosphoribosyltransferase, the first committed step in de novo purine synthesis, and inhibits fibroblast growth factor-2 (FGF2)-induced cell proliferation.

(Methylmercaptopurine Riboside, NCI Thesaurus)

These tumors frequently show a constitutive activation of the receptor tyrosine kinase-Ras pathway, exhibiting activating mutations in the HRAS and fibroblast growth factor receptor 3 (FGFR3) genes.

(Bladder Cancer Pathway, NCI Thesaurus/KEGG)

It is characterized by the presence of spindle-shaped fibroblasts and collagenous stroma formation in a herringbone growth pattern.

(Bone Fibrosarcoma, NCI Thesaurus)

Migration of cells is involved in essential functions such as development, invasiveness of cancer cells, leukocyte movement toward chemotactic signals, and fibroblast response to injury.

(Cell Migration Pathway, NCI Thesaurus/BIOCARTA)

Notably, 51 of the 57 genetic variants influence and regulate human lung fibroblast cells, a type of cell producing scar tissue in the lungs.

(Researchers identify genetic variations linked to oxygen drops during sleep, National Institutes of Health)