FATTY LIVER

Pronunciation (US):

(GB):

IPA (US):

 Dictionary entry overview: What does fatty liver mean? 

• FATTY LIVER (noun)
  The noun FATTY LIVER has 1 sense:

1. yellow discoloration as a result of the accumulation of certain fats (triglycerides) in the liver; can be caused by alcoholic cirrhosis or pregnancy or exposure to certain toxins

  Familiarity information: FATTY LIVER used as a noun is very rare.

 Dictionary entry details 

• FATTY LIVER (noun)

Sense 1

Meaning:

Yellow discoloration as a result of the accumulation of certain fats (triglycerides) in the liver; can be caused by alcoholic cirrhosis or pregnancy or exposure to certain toxins

Classified under:

Nouns denoting stable states of affairs

Hypernyms ("fatty liver" is a kind of...):

liver disease (a disease affecting the liver)

 Context examples 

New findings from mouse models reveal that the type of immune response that helps maintain healthy metabolism in fatty tissues, called type 2 immunity, also drives obesity-induced nonalcoholic fatty liver disease (NAFLD).

(NIH study sheds light on immune responses driving obesity-induced liver disease, National Institutes of Health)

Currently, some imaging tools like ultrasound or magnetic resonance imaging can help identify people with fatty livers, but these techniques often provide less detailed information.

(High-Fat, High-Sugar Diet Causes Lasting Harmful Effects on Liver, The Titi Tudorancea Bulletin)

But chronic damage in conditions such as alcohol abuse, fatty liver disease and certain viral infections, leads to impaired regeneration and cirrhosis (scarring), with eventual loss of liver function.

(Regeneration mechanism discovered in mice could provide target for drugs to combat chronic liver disease, University of Cambridge)

The researchers note that CD8 + T cells could potentially be used as markers for the progression of fatty liver disease, which is expected to become the leading indication for liver transplantation within the next one or two decades.

(When Liver Immune Cells Turn Bad, The Titi Tudorancea Bulletin)

The findings also might shed light on more common disorders such as fatty liver disease, obesity and diabetes by uncovering similarities in how MMA and these disorders affect energy metabolism and, more specifically, the function of mitochondria, the cells’ energy powerhouses.

(Elevated hormone flags liver problems in mice with methylmalonic acidemia, National Institutes of Health)

Patients with nonalcoholic fatty liver disease (NAFLD) develop an accumulation of excess fat in their livers.

(High-Fat, High-Sugar Diet Causes Lasting Harmful Effects on Liver, The Titi Tudorancea Bulletin)

In further investigations of human liver cells from nearly 50 donor tissues of humans with varying degrees of body mass index (BMI) and liver fat, higher levels of CD8+ T cells were linked with higher levels of blood sugar or more advanced fatty liver disease.

(When Liver Immune Cells Turn Bad, The Titi Tudorancea Bulletin)

The work, led by scientists at the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, shows that the inflammatory environment in the fatty liver is more complex than previously thought.

(NIH study sheds light on immune responses driving obesity-induced liver disease, National Institutes of Health)