FACTOR XII

Pronunciation (US):

(GB):

 Dictionary entry overview: What does factor XII mean? 

• FACTOR XII (noun)
  The noun FACTOR XII has 1 sense:

1. coagulation factor whose deficiency results in prolongation of clotting time of venous blood

  Familiarity information: FACTOR XII used as a noun is very rare.

 Dictionary entry details 

• FACTOR XII (noun)

Sense 1

Meaning:

Coagulation factor whose deficiency results in prolongation of clotting time of venous blood

Classified under:

Nouns denoting substances

Synonyms:

factor XII; Hageman factor

Hypernyms ("factor XII" is a kind of...):

clotting factor; coagulation factor (any of the factors in the blood whose actions are essential for blood coagulation)

 Context examples 

This cascade begins with the activation of factor XII and the release of platelet factor 3 (PF3) from damaged platelets.

(Intrinsic Prothrombin Activation Pathway, NCI Thesaurus/BIOCARTA)

An absence or reduced level of blood coagulation factor XII.

(Hereditary Factor XII Deficiency, NLM, Medical Subject Headings)

A rare autosomal recessive inherited bleeding disorder caused by deficiency of coagulation factor XII.

(Hereditary Factor XII Deficiency, NCI Thesaurus)

This allele, which encodes coagulation factor XII protein, plays a role in coagulation, fibrinolysis, and the generation of bradykinin and angiotensin.

(F12 wt Allele, NCI Thesaurus)

Coagulation factor XII ( 615 aa, ~68 kDa) is encoded by the human F12 gene.

(Coagulation Factor XII, NCI Thesaurus)

Activated factor XII cleaves and actives factor XI and prekallikrein (PK).

(Intrinsic Prothrombin Activation Pathway, NCI Thesaurus/BIOCARTA)