FACTOR IX

Pronunciation (US):

(GB):

 Dictionary entry overview: What does factor IX mean? 

• FACTOR IX (noun)
  The noun FACTOR IX has 1 sense:

1. coagulation factor whose absence is associated with hemophilia B

  Familiarity information: FACTOR IX used as a noun is very rare.

 Dictionary entry details 

• FACTOR IX (noun)

Sense 1

Meaning:

Coagulation factor whose absence is associated with hemophilia B

Classified under:

Nouns denoting substances

Synonyms:

Christmas factor; factor IX

Hypernyms ("factor IX" is a kind of...):

clotting factor; coagulation factor (any of the factors in the blood whose actions are essential for blood coagulation)

 Context examples 

A measurement of the biological activity of factor IX in a biological specimen.

(Factor IX Activity Measurement, NCI Thesaurus/CDISC)

The determination of the amount of factor IX present in a sample.

(Factor IX Measurement, NCI Thesaurus)

A measurement of the factor IX in a biological specimen.

(Factor IX Measurement, NCI Thesaurus/CDISC)

An X-linked inherited bleeding disorder caused by deficiency of the coagulation factor IX.

(Hemophilia B, NCI Thesaurus)

Alterations of this gene, including point mutations, insertions and deletions, cause factor IX deficiency.

(F9 wt Allele, NCI Thesaurus)

The determination of the amount of the biological activity of factor IX in a sample.

(Factor IX Activity Measurement, NCI Thesaurus)

People with missing or low levels of factor IX bleed longer than healthy people.

(Gene Therapy Used to Treat Hemophilia, NIH)

Inherited coagulation factor-deficient hemophilias include hemophilia A or classic hemophilia (factor VIII deficiency) hemophilia B or Christmas disease (factor IX deficiency), and hemophilia C (factor XI deficiency).

(Hemophilia, NCI Thesaurus)

A deficiency of blood coagulation factor IX inherited as an X-linked disorder. (Also known as Christmas Disease, after the first patient studied in detail, not the holy day.) Historical and clinical features resemble those in classic hemophilia (HEMOPHILIA A), but patients present with fewer symptoms.

(Hemophilia B, NLM, Medical Subject Headings)

Within 4 months of receiving the modified gene therapy, the patients’ blood levels of factor IX activity increased from less than 1% of normal to between 1% and 6% of normal.

(Gene Therapy Used to Treat Hemophilia, NIH)