EXTRINSIC

Pronunciation (US):

(GB):

IPA (US):

 Dictionary entry overview: What does extrinsic mean? 

• EXTRINSIC (adjective)
  The adjective EXTRINSIC has 1 sense:

1. not forming an essential part of a thing or arising or originating from the outside

  Familiarity information: EXTRINSIC used as an adjective is very rare.

 Dictionary entry details 

• EXTRINSIC (adjective)

Sense 1

Meaning:

Not forming an essential part of a thing or arising or originating from the outside

Context example:

looking for extrinsic aid

Similar:

adventitious (associated by chance and not an integral part)

adscititious (added or derived from something outside; not inherent)

alien; foreign (not contained in or deriving from the essential nature of something)

external; extraneous; outside (coming from the outside)

extraneous (not essential)

Also:

inessential; unessential (not basic or fundamental)

Antonym:

intrinsic (belonging to a thing by its very nature)

 Context examples 

In addition, this agent inhibits both the extrinsic and intrinsic coagulation cascades, preventing blood clot formation.

(Factor VIIa Inhibitor PCI-27483, NCI Thesaurus)

The prothrombin activator in the extrinsic pathway is very similar to the activator in the intrinsic pathway.

(Extrinsic Prothrombin Activation Pathway, NCI Thesaurus/BIOCARTA)

Active thrombin is produced by the cleavage of prothrombin in the intrinsic thrombin activation pathway or the extrinsic thrombin activation pathway.

(Fibrinolysis Pathway, NCI Thesaurus/BIOCARTA)

A measure of the extrinsic pathway of coagulation.

(International Normalized Ratio of Prothrombin Time, NCI Thesaurus)

The prothrombin activator in the intrinsic pathway is very similar to the activator in the extrinsic pathway.

(Intrinsic Prothrombin Activation Pathway, NCI Thesaurus/BIOCARTA)

Class difference was the only difference, and class was extrinsic.

(Martin Eden, by Jack London)

Mimicking the natural ligand TRAIL (tumor necrosis factor-related apoptosis inducing ligand), apomab binds to DR5, which may directly activate the extrinsic apoptosis pathway and indirectly induce the intrinsic apoptosis pathway in tumor cells.

(Apomab, NCI Thesaurus)

Heat- and storage-stable plasma protein that is activated by tissue thromboplastin to form factor VIIa in the extrinsic pathway of blood coagulation.

(Coagulation Factor VII, NLM, Medical Subject Headings)

The 2 major pathways of apoptosis are the extrinsic (Fas and other TNFR superfamily members and ligands) and the intrinsic (mitochondria-associated) pathways, both of which are found in the cytoplasm.

(Apoptosis Pathway, NCI Thesaurus/KEGG)

XIAP interferes with both the intrinsic and extrinsic program-death signaling pathways, which may render tumor cells resistant to apoptosis.

(AEG35156, NCI Thesaurus)