EXOSTOSIS (exostoses)

Pronunciation (US):

(GB):

Irregular inflected form: exostoses   

 Dictionary entry overview: What does exostosis mean? 

• EXOSTOSIS (noun)
  The noun EXOSTOSIS has 1 sense:

1. a benign outgrowth from a bone (usually covered with cartilage)

  Familiarity information: EXOSTOSIS used as a noun is very rare.

 Dictionary entry details 

• EXOSTOSIS (noun)

Sense 1

Meaning:

A benign outgrowth from a bone (usually covered with cartilage)

Classified under:

Nouns denoting stable states of affairs

Hypernyms ("exostosis" is a kind of...):

growth ((pathology) an abnormal proliferation of tissue (as in a tumor))

 Context examples 

Certain allelic variants of the EXT1 gene cause multiple exostoses type I.

(EXT1 wt Allele, NCI Thesaurus)

Certain allelic variants of the EXT2 gene cause multiple exostoses type II.

(EXT2 wt Allele, NCI Thesaurus)

Hereditary disorder transmitted by autosomal dominant genes (EXT1-3) and characterized by multiple exostoses (multiple osteochondromas) near the ends of long bones.

(Hereditary Multiple Exostoses, NCI Thesaurus)

A phenotypic variant of ADENOMATOUS POLYPOSIS COLI featuring multiple colonic polyposis with malignant tendency, subcutaneous fibromata and lipomata, exostoses and osteomas of the skull and facial bones, and epidermal inclusion cysts.

(Gardner Syndrome, NLM, Medical Subject Headings)

Frequent in some GEM and mice infected with acutely transforming MuLV; Necropsy findings: Splenomegaly, generalized lymphadenopathy, usually with extensive spread to liver, kidney, and lungs, sometimes to meninges with skull exostoses and hind limb paralysis; leukemic form in about one third of cases; Cell size: Medium, uniform; Cytoplasm: Scant; Nuclei: Round or ovoid; chromatin fine; Nucleoli: Variable, often single, central and prominent but sometimes small and multiple; Mitoses: Numerous; Pattern: Diffuse, sometimes starry sky because of apoptosis.

(Mouse Precursor B Cell Lymphoblastic Lymphoma and Leukemia, NCI Thesaurus/MMHCC)