EWING'S SARCOMA

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 Dictionary entry overview: What does Ewing's sarcoma mean? 

• EWING'S SARCOMA (noun)
  The noun EWING'S SARCOMA has 1 sense:

1. malignant tumor in bone marrow (usually in the pelvis or in long bones)

  Familiarity information: EWING'S SARCOMA used as a noun is very rare.

 Dictionary entry details 

• EWING'S SARCOMA (noun)

Sense 1

Meaning:

Malignant tumor in bone marrow (usually in the pelvis or in long bones)

Classified under:

Nouns denoting stable states of affairs

Synonyms:

endothelial myeloma; Ewing's sarcoma; Ewing's tumor; Ewing's tumour

Hypernyms ("Ewing's sarcoma" is a kind of...):

sarcoma (a usually malignant tumor arising from connective tissue (bone or muscle etc.); one of the four major types of cancer)

 Context examples 

The more potent transcription activator allele of a transforming chimeric gene resulting from a t(11;22) translocation that is found frequently in Ewing's sarcoma and primitive neuroectodermal tumor (PNET).

(EWS/FLI 1 Type 2, NCI Thesaurus)

EWS/FLI 1 type 4 represents a potential target for antisense oligonucleotide therapy of Ewing's sarcoma and PNET.

(EWS/FLI 1 Type 4, NCI Thesaurus)

EWS/FLI1 is a fusion protein frequently found in patients with Ewing's sarcoma or primitive neuroectodermal tumors (PNET).

(EF-1 Peptide, NCI Thesaurus)

One allele of the transforming chimeric gene resulting from a t(11;22) translocation that is found frequently in patients with Ewing's sarcoma or primitive neuroectodermal tumors (PNET).

(EWS/FLI 1 Type 1, NCI Thesaurus)

A regimen consisting of cyclophosphamide and topotecan, used for the treatment of recurrent or refractory childhood Ewing's sarcoma.

(Cyclophosphamide-Topotecan Regimen, NCI Thesaurus)

An antisense oligonucleotide that targets the type 8 form of EWS/FLI-1, an oncogenic fusion gene found in Ewing's sarcoma and primitive neuro-ectodermal tumor that results from a t(11;22) chromosomal translocation.

(EWS/FLI 1 Type 8, NCI Thesaurus)

Daunorubicin is indicated in the treatment of a wide variety of cancers including acute non-lymphocytic leukemia, non-Hodgkin's lymphomas, Ewing's sarcoma, Wilms' tumor, and chronic myelocytic leukemia.

(Daunorubicin Citrate, NCI Thesaurus)

There are three types of bone cancer: • Osteosarcoma - occurs most often between ages 10 and 19. It is more common in the knee and upper arm. • Chondrosarcoma - starts in cartilage, usually after age 40 • Ewing's sarcoma - occurs most often in children and teens under 19.

(Bone Cancer, NIH: National Cancer Institute)

The type 4 form of EWS/FLI-1, an oncogenic fusion gene found in Ewing's sarcoma and primitive neuro-ectodermal tumor (PNET).

(EWS/FLI 1 Type 4, NCI Thesaurus)

Resulting from a t(11;22) chromosomal translocation, EWS/FLI 1 appears to play an integral role in the development of Ewing's sarcoma and PNET; the type 4 form of this gene has been shown to transform non-neoplastic cells.

(EWS/FLI 1 Type 4, NCI Thesaurus)