ERGOTAMINE

Pronunciation (US):

(GB):

 Dictionary entry overview: What does ergotamine mean? 

• ERGOTAMINE (noun)
  The noun ERGOTAMINE has 1 sense:

1. an alkaloid derived from ergot that is less toxic than ergot; causes constriction of blood vessels and is used to treat migraine

  Familiarity information: ERGOTAMINE used as a noun is very rare.

 Dictionary entry details 

• ERGOTAMINE (noun)

Sense 1

Meaning:

An alkaloid derived from ergot that is less toxic than ergot; causes constriction of blood vessels and is used to treat migraine

Classified under:

Nouns denoting substances

Hypernyms ("ergotamine" is a kind of...):

alkaloid (natural bases containing nitrogen found in plants)

 Context examples 

Ergotamine tartrate also blocks serotonin 5-HT1D receptors, thereby also causing vasoconstriction in cerebral blood vessels.

(Ergotamine Tartrate, NCI Thesaurus)

Ergotamine selectively binds and activates serotonin (5-HT) 1D receptors located on intracranial blood vessels, including those on arterio-venous anastomoses, thereby resulting in vasoconstriction and reducing the blood flow in cerebral arteries that may lead to relieve of vascular headaches.

(Ergotamine, NCI Thesaurus)

Ergotamine tartrate selectively binds to alpha-adrenergic receptors thereby stimulating vascular smooth muscle and causing vasoconstriction in both arteries and veins.

(Ergotamine Tartrate, NCI Thesaurus)

The tartrate salt form of ergotamine, an ergot alkaloid and adrenergic alpha agonist with vasoconstrictor activity.

(Ergotamine Tartrate, NCI Thesaurus)