EFFICACY

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 Dictionary entry overview: What does efficacy mean? 

• EFFICACY (noun)
  The noun EFFICACY has 1 sense:

1. capacity or power to produce a desired effect

  Familiarity information: EFFICACY used as a noun is very rare.

 Dictionary entry details 

• EFFICACY (noun)

Sense 1

Meaning:

Capacity or power to produce a desired effect

Classified under:

Nouns denoting attributes of people and objects

Synonyms:

efficaciousness; efficacy

Context example:

concern about the safety and efficacy of the vaccine

Hypernyms ("efficacy" is a kind of...):

effectiveness; effectivity; effectuality; effectualness (power to be effective; the quality of being able to bring about an effect)

Attribute:

efficacious (marked by qualities giving the power to produce an intended effect)

inefficacious (lacking the power to produce a desired effect)

Antonym:

inefficacy (a lack of efficacy)

Derivation:

efficacious (producing or capable of producing an intended result or having a striking effect)

efficacious (marked by qualities giving the power to produce an intended effect)

 Context examples 

The sulfo-SPDB linker prevents cleavage in the bloodstream and may improve this agent's efficacy in multidrug resistant tumor cells.

(Anti-FOLR1-Monoclonal Antibody-Maytansinoid Conjugate IMGN853, NCI Thesaurus)

The administration of the melphalan-flufenamide prodrug allows for enhanced efficacy and reduced toxicity compared to melphalan alone.

(Melphalan-Flufenamide Prodrug, NCI Thesaurus)

KLH is an immunogenic carrier and serves as an immunostimulant to improve antigenic immune recognition and T-cell responses and can be used to evaluate vaccine efficacy.

(Autologous Melanoma Lysate/KLH-Pulsed Autologous Dendritic Cell Vaccine, NCI Thesaurus)

The use of animals for testing the safety and efficacy of drugs or treatments.

(Animal Testing, NCI Thesaurus)

Furthermore, this agent also inhibits the drug efflux pump P-glycoprotein, which is overexpressed in some multi-drug resistant tumors, and may improve the efficacy of some antineoplastic agents.

(Nimodipine, NCI Thesaurus)

Oligonucleotide SPC2996 binds to and inactivates Bcl-2 mRNA, thereby inhibiting the expression of Bcl-2 protein, promoting tumor cell apoptosis, and potentially enhancing the efficacy of standard cytotoxic chemotherapy.

(Oligonucleotide SPC2996, NCI Thesaurus)

This agent may enhance the efficacy of standard cytotoxic chemotherapy.

(Oblimersen, NCI Thesaurus)

Antitumor agents that are activated by biological reduction and have selective efficacy against hypoxic solid tumors.

(Bioreductive Agent, NCI Thesaurus)

Inhibition of dihydropyrimidine dehydrogenase increases the biological half-life and efficacy of 5-Fluorouracil (5-FU).

(Dihydropyrimidine Dehydrogenase Inhibitor, NCI Thesaurus)

“There has been many a one, I fancy, overcome in the same way. I wonder who first discovered the efficacy of poetry in driving away love!”

(Pride and Prejudice, by Jane Austen)