English Dictionary

DYSTROPHY

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 Dictionary entry overview: What does dystrophy mean? 

DYSTROPHY (noun)
  The noun DYSTROPHY has 2 senses:

1. any of several hereditary diseases of the muscular system characterized by weakness and wasting of skeletal musclesplay

2. any degenerative disorder resulting from inadequate or faulty nutritionplay

  Familiarity information: DYSTROPHY used as a noun is rare.


 Dictionary entry details 


DYSTROPHY (noun)


Sense 1

Meaning:

Any of several hereditary diseases of the muscular system characterized by weakness and wasting of skeletal muscles

Classified under:

Nouns denoting stable states of affairs

Synonyms:

dystrophy; muscular dystrophy

Hypernyms ("dystrophy" is a kind of...):

congenital disease; genetic abnormality; genetic defect; genetic disease; genetic disorder; hereditary condition; hereditary disease; inherited disease; inherited disorder (a disease or disorder that is inherited genetically)

Hyponyms (each of the following is a kind of "dystrophy"):

Becker muscular dystrophy (a form of muscular dystrophy that sets in in adolescence or adulthood and progresses slowly but will affect all voluntary muscles; characterized by generalized weakness and muscle wasting that affects limb and trunk muscles first; similar to Duchenne's muscular dystrophy but less severe; inheritance is X-linked recessive (carried by females but affecting only males))

distal muscular dystrophy (a form of muscular dystrophy that sets in between 40 and 60 years of age and is characterized by weakness and wasting of the muscles of the hands and forearms and lower legs; inheritance is autosomal dominant)

Duchenne's muscular dystrophy; pseudohypertrophic dystrophy (the most common form of muscular dystrophy; inheritance is X-linked recessive (carried by females but affecting only males))

limb-girdle muscular dystrophy (an autosomal recessive form of muscular dystrophy that appears anywhere from late childhood to middle age; characterized by progressive muscular weakness beginning either in the shoulder or pelvic girdle; usually progresses slowly with cardiopulmonary complications in the later stages)

myotonia atrophica; myotonic dystrophy; myotonic muscular dystrophy; Steinert's disease (a severe form of muscular dystrophy marked by generalized weakness and muscular wasting that affects the face and feet and hands and neck; difficult speech and difficulty with the hands that spreads to the arms and shoulders and legs and hips; the onset can be any time from birth to middle age and the progression is slow; inheritance is autosomal dominant)

oculopharyngeal muscular dystrophy (a form of muscular dystrophy that usually begins between early adulthood and middle age and first affects muscles of the eyelid and throat; progresses slowly with swallowing problems common as the disease progresses; inheritance is autosomal dominant)


Sense 2

Meaning:

Any degenerative disorder resulting from inadequate or faulty nutrition

Classified under:

Nouns denoting stable states of affairs

Hypernyms ("dystrophy" is a kind of...):

degenerative disorder (condition leading to progressive loss of function)

Hyponyms (each of the following is a kind of "dystrophy"):

osteodystrophy (defective bone development; usually attributable to renal disease or to disturbances in calcium and phosphorus metabolism)


 Context examples 


A rare genetic disorder characterized by nail dystrophy, reticulated skin pigmentation especially on the neck and chest, and oral leukoplakia.

(Dyskeratosis Congenita, NCI Thesaurus)

Mutation of the gene is associated with Doyne honeycomb retinal dystrophy.

(EFEMP1 wt Allele, NCI Thesaurus)

The researchers want to determine whether the results of their research could become a therapeutic target for rare muscle diseases such as myopathies and muscular dystrophies.

(Researchers Discovered Proteins Essential to Development of Skeletal Muscle, The Titi Tudorancea Bulletin)

Mutation of the gene is associated with facioscapulohumeral muscular dystrophy and a chromosomal translocation t(4;19)(q35;q13) of this gene and the CIC gene is associated with soft tissue sarcoma.

(DUX4 wt Allele, NCI Thesaurus)

Mutation of the gene is associated with limb-girdle muscular dystrophy type 1E.

(DNAJB6 wt Allele, NCI Thesaurus)

An X-linked or autosomal dominant inherited muscular dystrophy.

(Emery-Dreifuss Muscular Dystrophy, NCI Thesaurus)

A group of autosomal recessive and less frequently autosomal dominant muscular dystrophies affecting the muscles of the hips and shoulders.

(Limb-Girdle Muscular Dystrophy, NCI Thesaurus)

Representative examples include myotonia congenita and myotonic dystrophy.

(Myotonic Disorder, NCI Thesaurus)

Associated conditions include OBESITY; ACROMEGALY; MYXEDEMA; micrognathia; MYOTONIC DYSTROPHY; adenotonsillar dystrophy; and NEUROMUSCULAR DISEASES.

(Obstructive Sleep Apnea Syndrome, NLM, Medical Subject Headings)

There is no cure for muscular dystrophy.

(Muscular Dystrophy, NIH: National Institute of Neurological Disorders and Stroke)



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