English Dictionary |
DOPA
Pronunciation (US): | (GB): |
IPA (US): |
Dictionary entry overview: What does dopa mean?
• DOPA (noun)
The noun DOPA has 1 sense:
1. amino acid that is formed in the liver and converted into dopamine in the brain
Familiarity information: DOPA used as a noun is very rare.
Dictionary entry details
Sense 1
Meaning:
Amino acid that is formed in the liver and converted into dopamine in the brain
Classified under:
Nouns denoting substances
Synonyms:
dihydroxyphenylalanine; dopa
Hypernyms ("dopa" is a kind of...):
amino acid; aminoalkanoic acid (organic compounds containing an amino group and a carboxylic acid group)
Hyponyms (each of the following is a kind of "dopa"):
Bendopa; Brocadopa; L-dopa; Larodopa; levodopa (the levorotatory form of dopa (trade names Bendopa and Brocadopa and Larodopa); as a drug it is used to treat Parkinson's disease)
Context examples
D-Phenylalanine is converted into tyrosine and tyrosine in turn is converted into L-dopa, norepinephrine, and epinephrine, three key neurotransmitters.
(D-Phenylalanine, NCI Thesaurus)
Carbidopa does not penetrate the blood brain barrier so that levodopa, after it reaches the brain, can be metabolized to dopamine by dopa decarboxylase where it exerts its effect on dopamine receptors.
(Carbidopa, NCI Thesaurus)
Carbidopa, a peripheral dopa decarboxylase inhibitor, is used as an adjunct with levodopa to prevent levodopa degradation to dopamine in extracerebral tissue, thereby decreasing the peripheral side effects of levodopa.
(Carbidopa Anhydrous, NCI Thesaurus)
Carbidopa is a peripheral dopa decarboxylase inhibitor that is used as an adjunct to levodopa administration to prevent peripheral biosynthesis of levodopa to dopamine, thereby reducing peripheral side effects.
(Carbidopa, NCI Thesaurus)
A hydrazine derivative of dopa.
(Carbidopa, NCI Thesaurus)
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