DNA POLYMERASE

Pronunciation (US):

(GB):

 Dictionary entry overview: What does DNA polymerase mean? 

• DNA POLYMERASE (noun)
  The noun DNA POLYMERASE has 1 sense:

1. the enzyme responsible for DNA replication

  Familiarity information: DNA POLYMERASE used as a noun is very rare.

 Dictionary entry details 

• DNA POLYMERASE (noun)

Sense 1

Meaning:

The enzyme responsible for DNA replication

Classified under:

Nouns denoting substances

Hypernyms ("DNA polymerase" is a kind of...):

polymerase (an enzyme that catalyzes the formation of new DNA and RNA from an existing strand of DNA or RNA)

 Context examples 

Inhibition of DNA polymerase causes an inhibition of DNA synthesis and results in cell cycle arrest.

(DNA Polymerase Inhibitor, NCI Thesaurus)

DNA polymerase iota (740 aa, ~83 kDa) is encoded by the human POLI gene.

(DNA Polymerase Iota, NCI Thesaurus)

In eukaryotes, three DNA polymerases (alpha, delta, and epsilon) have been identified.

(DNA Replication Pathway, NCI Thesaurus/KEGG)

DNA polymerase epsilon catalytic subunit A (2286 aa, ~262 kDa) is encoded by the human POLE gene.

(DNA Polymerase Epsilon Catalytic Subunit A, NCI Thesaurus)

DNA polymerase beta (335 aa, ~38 kDa) is encoded by the human POLB gene.

(DNA Polymerase Beta, NCI Thesaurus)

DNA polymerase delta subunit 3 (466 aa, ~51 kDa) is encoded by the human POLD3 gene.

(DNA Polymerase Delta Subunit 3, NCI Thesaurus)

DNA-dependent DNA polymerases found in bacteria, animal and plant cells.

(DNA-directed DNA Polymerase, NLM, Medical Subject Headings)

Phosphonoacetic acid inhibits viral DNA polymerase and inhibits the synthesis of viral DNA.

(Phosphonoacetic Acid, NCI Thesaurus)

Pibenzimol binds to AT-specific sites in the minor groove of duplex DNA and inhibits topoisomerase I, and DNA polymerase, thereby preventing DNA replication.

(Pibenzimol, NCI Thesaurus)

Omaciclovir is selectively phosphorylated by viral thymidine kinase to its monophosphate form and is further modified to a triphosphate, which is an inhibitor of VZV DNA polymerase.

(Omaciclovir, NCI Thesaurus)