DIVALENT

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 Dictionary entry overview: What does divalent mean? 

• DIVALENT (adjective)
  The adjective DIVALENT has 1 sense:

1. having a valence of two or having two valences

  Familiarity information: DIVALENT used as an adjective is very rare.

 Dictionary entry details 

• DIVALENT (adjective)

Sense 1

Meaning:

Having a valence of two or having two valences

Classified under:

Relational adjectives (pertainyms)

Synonyms:

bivalent; divalent

Domain category:

chemical science; chemistry (the science of matter; the branch of the natural sciences dealing with the composition of substances and their properties and reactions)

Pertainym:

valence ((chemistry) a property of atoms or radicals; their combining power given in terms of the number of hydrogen atoms (or the equivalent))

 Context examples 

A radiolabeled divalent histamine-succinyl-glycine (HSG) hapten-peptide linked with the macrocyclic chelator 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid (DOTA) to the radionuclide indium (In) 111.

(Indium In 111-DOTA-di-HSG Peptide IMP-288, NCI Thesaurus)

A tri-Fab bispecific monoclonal antibody (BiMoAb) divalent for the carcinoembryonic antigen (CEA) and monovalent for histamine-succinyl-glycine (HSG) peptide-hapten radiolabeled with iodine I 131 (I131) with antigen-binding and radioisotopic activities.

(Iodine I 131-Labeled Anti-CEA/Anti-HSG Bispecific Monoclonal Antibody TF2, NCI Thesaurus)

A radiolabeled divalent histamine-succinyl-glycine (HSG) hapten-peptide linked with the macrocyclic chelator 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid (DOTA) to the radionuclide lutetium (Lu) 177.

(Lutetium Lu 177-DOTA-di-HSG Peptide IMP-288, NCI Thesaurus)

This protein plays a role in the promotion of proliferation and differentiation of chondrocytes and also mediates heparin- and divalent cation-dependent cell adhesion in many different cell types.

(Connective Tissue Growth Factor, NCI Thesaurus)

Edetate, a heavy metal antagonist, chelates divalent and trivalent metals, forming soluble stable complexes which are readily excreted by the kidneys, thereby can be used to lower serum calcium concentrations.

(Edetate Disodium, NCI Thesaurus)

A tri-Fab bispecific monoclonal antibody (BiMoAb) divalent for the carcinoembryonic antigen (CEA) and monovalent for histamine-succinyl-glycine (HSG) peptide-hapten.

(Anti-CEA/Anti-HSG Bispecific Monoclonal Antibody TF2, NCI Thesaurus)

Exposure to divalent cadmium ions (Cd2+) is a known cancer risk factor, but the molecular mechanisms responsible for the inappropriate induction of cellular proliferation by cadmium are still being figured out.

(Cadmium Induction Pathway, NCI Thesaurus/BIOCARTA)

Inhibited by chelating agents; requires divalent cations for activity.

(Aryldialkylphosphatase, NCI Thesaurus)

Phosphoric acid is a sequestering agent which binds many divalent cations, including Fe++, Cu++, Ca++, and Mg++.

(Phosphoric acid, NCI Thesaurus)

Magnesium is a divalent cation essential for a number of biochemical processes involved in nerve signaling, bone mineralization and muscle contractions.

(Magnesium Acetate, NCI Thesaurus)