DISRUPT

Pronunciation (US):

(GB):

IPA (US):

 Dictionary entry overview: What does disrupt mean? 

• DISRUPT (verb)
  The verb DISRUPT has 3 senses:

1. make a break in

2. throw into disorder

3. interfere in someone else's activity

  Familiarity information: DISRUPT used as a verb is uncommon.

 Dictionary entry details 

• DISRUPT (verb)

Present simple: I / you / we / they disrupt    ... he / she / it disrupts   
Past simple: disrupted   
Past participle: disrupted   
-ing form: disrupting   

Sense 1

Meaning:

Make a break in

Classified under:

Verbs of telling, asking, ordering, singing

Synonyms:

break up; cut off; disrupt; interrupt

Context example:

We interrupt the program for the following messages

Hypernyms (to "disrupt" is one way to...):

break; break off; discontinue; stop (prevent completion)

Troponyms (each of the following is one way to "disrupt"):

cut; cut off (cease, stop)

punctuate (interrupt periodically)

break (interrupt the flow of current in)

put aside; put away (turn away from and put aside, perhaps temporarily)

break; intermit; pause (cease an action temporarily)

barge in; break in; butt in; chime in; chisel in; cut in; put in (break into a conversation)

burst in on; burst upon (spring suddenly)

heckle (challenge aggressively)

come in; inject; interject; interpose; put in; throw in (to insert between other elements)

block; jam (interfere with or prevent the reception of signals)

stop; stop over (interrupt a trip)

take off; take time off (take time off from work; stop working temporarily)

Sentence frames:

Somebody ----s
Somebody ----s something
Somebody ----s somebody
Something ----s somebody
Something ----s something

Derivation:

disruption (an act of delaying or interrupting the continuity)

Sense 2

Meaning:

Throw into disorder

Classified under:

Verbs of size, temperature change, intensifying, etc.

Context example:

This event disrupted the orderly process

Sentence frames:

Somebody ----s something
Somebody ----s somebody
Something ----s somebody
Something ----s something

Derivation:

disruption (the act of causing disorder)

disruptive (characterized by unrest or disorder or insubordination)

Sense 3

Meaning:

Interfere in someone else's activity

Classified under:

Verbs of size, temperature change, intensifying, etc.

Synonyms:

disrupt; interrupt

Context example:

Please don't interrupt me while I'm on the phone

Hypernyms (to "disrupt" is one way to...):

barge in; break in; butt in; chime in; chisel in; cut in; put in (break into a conversation)

Troponyms (each of the following is one way to "disrupt"):

cut in (interrupt a dancing couple in order to take one of them as one's own partner)

cut short (cause to end earlier than intended)

Sentence frames:

Somebody ----s something
Somebody ----s somebody

Derivation:

disruption (an act of delaying or interrupting the continuity)

 Context examples 

In biology, refers to viruses that do not kill infected cells by disrupting their plasma membranes.

(Nonlytic, NCI Dictionary)

In addition, curcumin and some other polyphenols disrupt cell signal transduction pathways involved in carcinogenesis.

(Olive Oil Extract/Curcumin-based Capsule, NCI Thesaurus)

A synthetic water-soluble analogue of combretastatin A4, derived from the South African willow bush (Combretum caffrum), with potential vascular-disrupting and antineoplastic activities.

(Ombrabulin, NCI Thesaurus)

Nocodazole binds to beta-tubulin and disrupts microtubule assembly/disassembly dynamics.

(Nocodazole, NCI Thesaurus)

This calcium flux induces binding of calmodulin to NOSIII, whereas the NOSIII-caveolin-1 interaction is disrupted.

(Nitric Oxide Pathway, NCI Thesaurus/BIOCARTA)

Treatment of cancer that utilizes antimetabolite substances to disrupt DNA, RNA, or protein synthesis.

(Antimetabolite Chemotherapy, NCI Thesaurus)

MYB Oncogene Protein disrupts normal cell function.

(Myb Oncogene Protein, NCI Thesaurus)

Omiganan pentahydrochloride, an analog of indolicidin, acts by disrupting bacterial cytoplasmic membranes and has been tested in a topical gel for the prevention of catheter-related bloodstream infections.

(Omiganan Pentahydrochloride, NCI Thesaurus)

This may disrupt tumor endothelial cell function and inhibit tumor angiogenesis, eventually leading to an inhibition of tumor cell proliferation.

(Anti-ALK-1 Monoclonal Antibody PF-03446962, NCI Thesaurus)

Specific haematopoietic transcription factors are crucial for differentiation to particular lineages during normal differentiation, but are frequently disrupted in AML.

(Acute Myeloid Leukemia Pathway, NCI Thesaurus/KEGG)