English Dictionary

DIFFERENTIATED

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IPA (US): 

 Dictionary entry overview: What does differentiated mean? 

DIFFERENTIATED (adjective)
  The adjective DIFFERENTIATED has 2 senses:

1. made different (especially in the course of development) or shown to be differentplay

2. exhibiting biological specialization; adapted during development to a specific function or environmentplay

  Familiarity information: DIFFERENTIATED used as an adjective is rare.


 Dictionary entry details 


DIFFERENTIATED (adjective)


Sense 1

Meaning:

Made different (especially in the course of development) or shown to be different

Context example:

the regionally differentiated results

Antonym:

undifferentiated (not differentiated)


Sense 2

Meaning:

Exhibiting biological specialization; adapted during development to a specific function or environment

Similar:

specialised; specialized (developed or designed for a special activity or function)

Domain category:

biological science; biology (the science that studies living organisms)


 Context examples 


Invasive gland forming lesions in human associated with HGPIN are designated as moderately differentiated.

(Moderately Differentiated Invasive Adenocarcinoma of the Mouse Prostate Gland, NCI Thesaurus/MMHCC)

After binding of monoclonal antibody MGA271 to an as of yet not elucidated target expressed on CSCs and differentiated tumor cells, this agent may induce an antibody-dependent cell-mediated cytotoxicity (ADCC) against CSCs.

(Monoclonal Antibody MGA271, NCI Thesaurus)

Comment: Leukemia in which neoplastic cells are well differentiated; less than 20% immature forms/blasts in hematopoietic tissue

(Mouse MPD-like Myeloid Leukemia, NCI Thesaurus/MMHCC)

It includes the following types: keratinizing squamous cell carcinoma, nonkeratinizing carcinoma (differentiated and undifferentiated), basaloid squamous cell carcinoma, and papillary adenocarcinoma.

(Nasopharyngeal Carcinoma, NCI Thesaurus)

They tend to grow and spread at a faster rate than well differentiated tumor cells.

(Moderately Differentiated, NCI Thesaurus)

Individual chromosomes can be discerned and differentiated morphologically.

(Mitotic Chromosome, NCI Thesaurus)

A well differentiated, intermediate grade tumor with neuroendocrine differentiation that arises from the appendix.

(Appendix Neuroendocrine Tumor G2, NCI Thesaurus)

An aggressive, poorly differentiated neuroendocrine malignant neoplasm arising from the wall of the appendix.

(Appendix Small Cell Neuroendocrine Carcinoma, NCI Thesaurus)

Utterly differentiated creatures that they were, they were lonely in their misery, and though the misery was tacitly ignored, it was the bond that drew them together.

(Martin Eden, by Jack London)

A rare, well differentiated, cytologically benign ameloblastoma which paradoxically metastasizes.

(Metastasizing Ameloblastoma, NCI Thesaurus)



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