DEREGULATE

Pronunciation (US):

(GB):

IPA (US):

 Dictionary entry overview: What does deregulate mean? 

• DEREGULATE (verb)
  The verb DEREGULATE has 1 sense:

1. lift the regulations on

  Familiarity information: DEREGULATE used as a verb is very rare.

 Dictionary entry details 

• DEREGULATE (verb)

Present simple: I / you / we / they deregulate    ... he / she / it deregulates   
Past simple: deregulated   
Past participle: deregulated   
-ing form: deregulating   

Sense 1

Meaning:

Lift the regulations on

Classified under:

Verbs of political and social activities and events

Hypernyms (to "deregulate" is one way to...):

exempt; free; relieve (grant relief or an exemption from a rule or requirement to)

Sentence frame:

Somebody ----s something

Antonym:

regulate (bring into conformity with rules or principles or usage; impose regulations)

Derivation:

deregulating; deregulation (the act of freeing from regulation (especially from governmental regulations))

 Context examples 

ICOVIR-5, a virus derived from wild-type human adenovirus serotype 5 (Had5), has been modified to selectively replicate in tumor cells that have a deregulated retinoblastoma/E2F pathway.

(Oncolytic Adenovirus ICOVIR5-infected Autologous Mesenchymal Stem Cells, NCI Thesaurus)

Raf protein kinases play a key role in the RAF/MEK/ERK signaling pathway, which is often deregulated in human cancers and plays a key role in tumor cell proliferation and survival.

(pan-RAF Kinase Inhibitor MLN2480, NCI Thesaurus)

Deregulated ETS-gene expression or chimeric ETS-proteins are associated with leukemias, some tumors, invasion and metastasis.

(ETS Domain, NCI Thesaurus)

Deregulated cdk5 hyperphosphorylates tau promoting cell death in neurons.

(Calpain-2 Cell Motility Pathway, NCI Thesaurus/BIOCARTA)

The AKT signaling pathway is often deregulated in cancer and is associated with tumor cell proliferation, survival and migration.

(AKT 1/2 Inhibitor BAY1125976, NCI Thesaurus)

Adenosine A3 receptor agonist CF102 selectively binds to and activates the cell surface-expressed A3AR, deregulating Wnt and NF-kB signal transduction pathways downstream, which may result in apoptosis of A3AR-expressing tumor cells.

(Adenosine A3 Receptor Agonist CF102, NCI Thesaurus)