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DEOXYADENOSINE
Pronunciation (US): | (GB): |
Dictionary entry overview: What does deoxyadenosine mean?
• DEOXYADENOSINE (noun)
The noun DEOXYADENOSINE has 1 sense:
1. a nucleoside component of DNA; composed of adenosine and deoxyribose
Familiarity information: DEOXYADENOSINE used as a noun is very rare.
Dictionary entry details
Sense 1
Meaning:
A nucleoside component of DNA; composed of adenosine and deoxyribose
Classified under:
Nouns denoting substances
Hypernyms ("deoxyadenosine" is a kind of...):
nucleoside (a glycoside formed by partial hydrolysis of a nucleic acid)
Context examples
This compound also forms mutagenic DNA adducts when it reacts with deoxyadenosine and deoxyguanosine in DNA.
(Malondialdehyde, NCI Thesaurus)
Fudarabine is preferentially transported into malignant cells and metabolized by deoxycytidine kinase to its active form, 2-fluoro-ara-ATP; 2-fluoro-ara-ATP competes directly with deoxyadenosine triphosphate (dATP) and inhibits alpha DNA polymerase, RNA reductase, and DNA primase, which may result in inhibition of DNA synthesis and cell death.
(Oral Fludarabine Phosphate, NCI Thesaurus)
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