DEMYELINATE

Pronunciation (US):

(GB):

 Dictionary entry overview: What does demyelinate mean? 

• DEMYELINATE (verb)
  The verb DEMYELINATE has 1 sense:

1. destroy the myelin sheath of

  Familiarity information: DEMYELINATE used as a verb is very rare.

 Dictionary entry details 

• DEMYELINATE (verb)

Present simple: I / you / we / they demyelinate    ... he / she / it demyelinates   
Past simple: demyelinated   
Past participle: demyelinated   
-ing form: demyelinating   

Sense 1

Meaning:

Destroy the myelin sheath of

Classified under:

Verbs of sewing, baking, painting, performing

Context example:

the disease demyelinated the nerve fibers

Hypernyms (to "demyelinate" is one way to...):

destroy; destruct (do away with, cause the destruction or undoing of)

Sentence frame:

Something ----s something

 Context examples 

Infection is not accompanied by any apparent illness but serious demyelinating disease can appear later, probably following reactivation of latent virus.

(JC Virus, NLM, Medical Subject Headings)

A rare congenital demyelinating disorder affecting the central nervous system.

(Diffuse Cerebral Sclerosis of Schilder, NCI Thesaurus)

Experimental allergic encephalomyelitis (EAE) is used as an animal model for demyelinating diseases of the human central nervous system such as multiple sclerosis.

(Experimental Allergic Encephalomyelitis, NCI Thesaurus)

It is often caused by a dorsal midbrain neoplasm, commonly a pinealoma, but may also be attributable to demyelinating diseases or stroke.

(Parinaud Syndrome, NCI Thesaurus)

A pathologic astrocyte in which the cell body swells and contains glial filaments and an eccentric nucleus; seen particularly in demyelinating and neoplastic conditions.

(Gemistocytic Neoplastic Astrocyte, NCI Thesaurus)

Following intravenous administration, gadobutrol may increase MRI sensitivity for the detection of tumors and inflammatory and demyelinating diseases of the central nervous system (CNS) that are associated with areas with blood-brain barrier defects due to altered perfusion or an enlarged extracellular space.

(Gadobutrol, NCI Thesaurus)

It is characterized by a demyelinating destructive lesion affecting an entire brain lobe or hemisphere.

(Diffuse Cerebral Sclerosis of Schilder, NCI Thesaurus)

An autoimmune demyelinating disease of the central nervous system that is produced experimentally in animals by the injection of homogenized brain or spinal cord in Freund's adjuvant.

(Experimental Allergic Encephalomyelitis, NCI Thesaurus)