DELETERIOUS

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 Dictionary entry overview: What does deleterious mean? 

• DELETERIOUS (adjective)
  The adjective DELETERIOUS has 1 sense:

1. harmful to living things

  Familiarity information: DELETERIOUS used as an adjective is very rare.

 Dictionary entry details 

• DELETERIOUS (adjective)

Sense 1

Meaning:

Harmful to living things

Synonyms:

deleterious; hurtful; injurious

Context example:

deleterious chemical additives

Similar:

harmful (causing or capable of causing harm)

 Context examples 

Any event, process, or activity that produces a deleterious alteration of DNA.

(Pathologic Mutagenesis, NCI Thesaurus)

A biologic function or a process having an abnormal or deleterious effect at the subcellular, cellular, multicellular, or organismal level.

(Pathologic Process, NCI Thesaurus)

Molecular variants of the desired biological product formed during manufacture and/or storage, which are active and have no deleterious effect on the safety and efficacy of the drug substance or drug product.

(Pharmaceutical Product-related Substance, NCI Thesaurus)

Fragmentation changes how ecosystems function, reduces the amounts of nutrients retained and the amount of carbon sequestered and has other deleterious effects.

(Shrinking habitats have adverse effects on world ecosystems, NSF)

GM2 containing vaccines have been shown to elicit antibodies production in melanoma patients without deleterious effects associated with an immune response to GM2.

(Ganglioside GM2, NCI Thesaurus)

The research in this category is directed toward understanding the nature of the chemicals involved, and the reaction mechanisms behind, the deleterious effects of tobacco smoke and smokeless tobacco products.

(Experimental Tobacco Carcinogenesis, NCI Thesaurus)

Issue associated with a deleterious change in the chemical structure, physical properties, or appearance in the materials that are used in device construction.

(Medical Device Material Degradation, Food and Drug Administration)

Positive selection is where mutations that provide an organism with a particular advantage are more likely to be passed down generations; negative selection is where mutations that are likely to have a deleterious effect are less likely to be passed on.

(The curious tale of the cancer ‘parasite’ that sailed the seas, University of Cambridge)

Nonsense-Mediated Decay is the widely conserved process in eukaryotes whereby certain alternatively spliced RNAs, some selenoprotein mRNAs, and nonsense or frame-shift mutations that result in premature translation termination signal rapid mRNA degradation; the mechanism that eliminates mRNAs with premature termination codons, reducing the accumulation of deleterious proteins and their effects.

(Nonsense-Mediated Decay, NCI Thesaurus)

Germline genetic testing method targeted to detect a specific mutation (such as a deleterious MSH2 mutation previously identified in a family), panel of mutations (such as the 3 BRCA mutations comprising the founder mutation panel for individuals of Ashkenazi Jewish ancestry) or type of mutation (such as a large deletions or insertions in the BRCA1 gene).

(Mutation Analysis, NCI Dictionary)