DECARBOXYLATION

Pronunciation (US):

(GB):

 Dictionary entry overview: What does decarboxylation mean? 

• DECARBOXYLATION (noun)
  The noun DECARBOXYLATION has 1 sense:

1. the process of removing a carboxyl group from a chemical compound (usually replacing it with hydrogen)

  Familiarity information: DECARBOXYLATION used as a noun is very rare.

 Dictionary entry details 

• DECARBOXYLATION (noun)

Sense 1

Meaning:

The process of removing a carboxyl group from a chemical compound (usually replacing it with hydrogen)

Classified under:

Nouns denoting natural processes

Hypernyms ("decarboxylation" is a kind of...):

chemical action; chemical change; chemical process ((chemistry) any process determined by the atomic and molecular composition and structure of the substances involved)

Derivation:

decarboxylate (remove a carboxyl group from (a chemical compound))

decarboxylate (lose a carboxyl group)

 Context examples 

Histamine is synthesized in a single step from the amino acid histidine through decarboxylation.

(Neurotransmitter Biosynthesis Pathway, NCI Thesaurus/BIOCARTA)

One is irreversible oxidative phase in which glucose-6P is converted to ribulose-5P by oxidative decarboxylation, and NADPH is generated.

(Pentose Phosphate Cycle Pathway, NCI Thesaurus/KEGG)

Any substance that inhibits ornithine decarboxylase, an enzyme that catalyzes the decarboxylation of ornithine, the rate-limiting, commiting reaction in polyamine synthesis.

(Ornithine Decarboxylase Inhibitor, NCI Thesaurus)

An autosomal recessive inherited disorder with multiple forms of phenotypic expression, caused by a defect in the oxidative decarboxylation of branched-chain amino acids (AMINO ACIDS, BRANCHED-CHAIN).

(Maple Syrup Urine Disease, NLM, Medical Subject Headings)

Acetyl-CoA, another important precursor metabolite, is produced by oxidative decarboxylation of pyruvate.

(Glycolysis/Gluconeogenesis Pathway, NCI Thesaurus/KEGG)

This species is motile, indole and oxidase negative, catalase positive, negative for lysine decarboxylation, and does not reduce nitrate.

(Burkholderia gladioli, NCI Thesaurus)

In addition, alpha-lipoic acid exerts metal chelating capacities and functions as a cofactor in various mitochondrial enzyme complexes involved in the decarboxylation of alpha-keto acids.

(Alpha-lipoic acid, NCI Thesaurus)

Dopamine is a naturally occurring catecholamine formed by decarboxylation of dehydroxyphenylalanine and a precursor of norepinephrine and epinephrine.

(Dopamine, NCI Thesaurus)

Any substance that inhibits orotidine 5'-phosphate decarboxylase (orotidylate decarboxylase), an enzyme that catalyzes the decarboxylation of orotidine monophosphate to form uridine monophosphate and is required for the de novo synthesis of uridine and pyrimidines.

(Orotidylate Decarboxylase Inhibitor, NCI Thesaurus)

Histamine Degradation consists of conjugation, transport, oxidation, or enzymatic breakdown of a decarboxylation product of histidine (histamine), found particularly in mast cells and basophils, and involved in capillary dilation and permeability; blood pressure decrease; smooth muscle contraction; gastric secretion; heart rate acceleration; immediate hypersensitivity; and central neurotransmission.

(Histamine Degradation, NCI Thesaurus)