DEAMINATION

Pronunciation (US):

(GB):

 Dictionary entry overview: What does deamination mean? 

• DEAMINATION (noun)
  The noun DEAMINATION has 1 sense:

1. removal of the amino radical from an amino acid or other amino compound

  Familiarity information: DEAMINATION used as a noun is very rare.

 Dictionary entry details 

• DEAMINATION (noun)

Sense 1

Meaning:

Removal of the amino radical from an amino acid or other amino compound

Classified under:

Nouns denoting natural processes

Synonyms:

deamination; deaminization

Hypernyms ("deamination" is a kind of...):

chemical action; chemical change; chemical process ((chemistry) any process determined by the atomic and molecular composition and structure of the substances involved)

Derivation:

deaminate (remove the amino radical (usually by hydrolysis) from an amino compound; to perform deamination)

 Context examples 

In biological applications, hydrazine and its derivatives exhibit antidepressant properties by inhibiting monoamine oxidase (MAO), an enzyme that catalyzes the deamination and inactivation of certain stimulatory neurotransmitters such as norepinephrine and dopamine.

(Hydrazine, NCI Thesaurus)

This gene plays a role in both class-switch recombination in B-lymphocytes and cytidine deamination.

(AICDA Gene, NCI Thesaurus)

Any substance that inhibits monoamine oxidase (MAO), an enzyme that catalyzes the oxidative deamination of monoamines and plays a role in the inactivation of neurotransmitters.

(Monoamine oxidase inhibitor, NCI Thesaurus)

Pargyline selectively inhibits MAO type B, an enzyme catalyzing the oxidative deamination and inactivation of certain catecholamines, such as norepinephrine and dopamine, within the presynaptic nerve terminals.

(Pargyline, NCI Thesaurus)

Compared to gemcitabine alone, the emulsion allows for increased oral bioavailability and decreases its susceptibility to deamination and deactivation by cytidine deaminase.

(Gemcitabine Hydrochloride Emulsion, NCI Thesaurus)

Isocarboxazid blocks the breakdown (oxidative deamination) of biogenic amines by inhibiting MAO, thereby increasing the concentrations of norepinephrine and 5-hydroxytrytamine (5-HT) at central aminergic receptors.

(Isocarboxazid, NCI Thesaurus)

In addition, this formulation of gemcitabine may be less susceptible to deamination and deactivation by deoxycytidine deaminase.

(Gemcitabine Elaidate, NCI Thesaurus)

This protein is involved in the deamination of cytidine and deoxycytidine to uridine and deoxyuridine, respectively.

(Cytidine Deaminase, NCI Thesaurus)

The ammonia released through the deamination of amino acids is reacted to produce carbamoyl phosphate, a reaction catalyzed by carbamoyl phosphate synthase.

(Feeding Amino Groups into the Urea Cycle, NCI Thesaurus/BIOCARTA)

ADA, an enzyme that catalyzes the deamination of adenosine to inosine, plays a key role in the development and functioning of the immune system.

(EFS-ADA Lentiviral Vector-transduced CD34-positive Autologous Lymphocytes, NCI Thesaurus)