DAPSONE

Pronunciation (US):

(GB):

 Dictionary entry overview: What does dapsone mean? 

• DAPSONE (noun)
  The noun DAPSONE has 1 sense:

1. antibacterial drug used to treat leprosy and some kinds of skin diseases

  Familiarity information: DAPSONE used as a noun is very rare.

 Dictionary entry details 

• DAPSONE (noun)

Sense 1

Meaning:

Antibacterial drug used to treat leprosy and some kinds of skin diseases

Classified under:

Nouns denoting man-made objects

Hypernyms ("dapsone" is a kind of...):

antibacterial; antibacterial drug; bactericide (any drug that destroys bacteria or inhibits their growth)

 Context examples 

Dapsone's anti-inflammatory activities may contribute to the effects seen upon topical administration.

(Dapsone, NCI Thesaurus)

A sulfone drug that is converted to dapsone in the body.

(Glucosulfone Free Acid, NCI Thesaurus)

Dapsone is a type of antibacterial agent and a type of anti-inflammatory agent.

(Dapsone, NCI Dictionary)

The 5% gel preparation of dapsone, a synthetic derivative of diamino-sulfone with anti-inflammatory and anti-bacterial properties.

(Dapsone Gel, NCI Thesaurus)

A sodium salt form of acediasulfone, a long-acting prodrug of dapsone, used in the treatment of leprosy.

(Acediasulfone Sodium, NCI Thesaurus)

A long-acting prodrug of dapsone, used in the treatment of leprosy.

(Acediasulfone, NCI Thesaurus)

As a structural analog of p-aminobenzoic acid (PABA), dapsone inhibits dihydropteroate synthase (DHPS), an enzyme important in folate synthesis, resulting in a depletion of the folate pool and a reduction in the amount of thymidylate available for DNA synthesis.

(Dapsone, NCI Thesaurus)

Although the exact mechanism through which dapsone exerts its anti-inflammatory activity has yet to be fully elucidated, this agent interferes with the activation and oxidative damage of myeloperoxidase in neutrophils and inhibits the integrin-mediated adherence and chemotaxis of neutrophils.

(Dapsone, NCI Thesaurus)