CYTIDINE

Pronunciation (US):

(GB):

 Dictionary entry overview: What does cytidine mean? 

• CYTIDINE (noun)
  The noun CYTIDINE has 1 sense:

1. a nucleoside component of DNA; composed of cytosine and deoxyribose

  Familiarity information: CYTIDINE used as a noun is very rare.

 Dictionary entry details 

• CYTIDINE (noun)

Sense 1

Meaning:

A nucleoside component of DNA; composed of cytosine and deoxyribose

Classified under:

Nouns denoting substances

Synonyms:

cytidine; deoxycytidine

Hypernyms ("cytidine" is a kind of...):

nucleoside (a glycoside formed by partial hydrolysis of a nucleic acid)

 Context examples 

Inhibition of cytidine triphosphate synthetase interferes with DNA, RNA, and CTP biosynthesis and can cause cell cycle arrest.

(Cytidine Triphosphate Synthetase Inhibitor, NCI Thesaurus)

A cytidine antimetabolite analogue with potential antineoplastic activity.

(Decitabine, NCI Thesaurus)

Any substance that inhibits cytidine deaminase, an enzyme that scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

(Cytidine Deaminase Inhibitor, NCI Thesaurus)

This protein is involved in the deamination of cytidine and deoxycytidine to uridine and deoxyuridine, respectively.

(Cytidine Deaminase, NCI Thesaurus)

Upon administration, the cytidine analog RX-3117 is taken up by cells through a carrier-mediated transporter, phosphorylated by uridine cytidine kinase (UCK) and then further phosphorylated to its diphosphate (RX-DP) and triphosphate forms (RX-TP).

(Cytidine Analog RX-3117, NCI Thesaurus)

This protein is a member of the cytidine deaminase gene family and may play a role in editing mRNA, cellular growth and cell cycle control.

(DNA dC to dU-Editing Enzyme APOBEC-3G, NCI Thesaurus)

This agent is resistant to cytidine deaminase, hence may result in gradual release of decitabine both extra and intracellularly, leading to more prolonged exposures to decitabine.

(DNA Methyltransferase Inhibitor SGI-110, NCI Thesaurus)

An orally available prodrug of PSI-6130 which is a selective cytidine nucleoside analogue and non-cytotoxic hepatitis C virus (HCV) polymerase inhibitor.

(Mericitabine, NCI Thesaurus)

Examples of these include cytidine, uridine, adenosine, guanosine, thymidine, inosine and others.

(Nucleoside, NCI Thesaurus)

FdCyd is coadministered with tetrahydrouridine (THU), an inhibitor of cytidine/deoxycytidine deaminase, which prevents FdCyd breakdown and increases its efficacy.

(Fluorine F 18 5-Fluoro-2-deoxycytidine, NCI Thesaurus)