COX-2 INHIBITOR

 Dictionary entry overview: What does Cox-2 inhibitor mean? 

• COX-2 INHIBITOR (noun)
  The noun COX-2 INHIBITOR has 1 sense:

1. an anti-inflammatory drug that fights pain and blocks Cox-2 activity without impeding the activity of Cox-1; increases the risk of heart attacks

  Familiarity information: COX-2 INHIBITOR used as a noun is very rare.

 Dictionary entry details 

• COX-2 INHIBITOR (noun)

Sense 1

Meaning:

An anti-inflammatory drug that fights pain and blocks Cox-2 activity without impeding the activity of Cox-1; increases the risk of heart attacks

Classified under:

Nouns denoting man-made objects

Context example:

Cox-2 inhibitors reduce the symptoms of arthritis without endangering the stomach and kidneys

Hypernyms ("Cox-2 inhibitor" is a kind of...):

anti-inflammatory; anti-inflammatory drug (a medicine intended to reduce inflammation)

Hyponyms (each of the following is a kind of "Cox-2 inhibitor"):

Celebrex; celecoxib (a Cox-2 inhibitor (trade name Celebrex) that relieves pain and inflammation without harming the digestive tract)

rofecoxib; Vioxx (a Cox-2 inhibitor (trade name Vioxx) that relieves pain and inflammation without harming the digestive tract; voluntarily withdrawn from the market in 2004)

Bextra; valdecoxib (a Cox-2 inhibitor (trade name Bextra) that relieves pain and inflammation without harming the digestive tract)

 Context examples 

Recent NSAIDS acting selectively as Cox-2 inhibitors like Vioxx are widely used for the treatment of arthritis and other inflammatory conditions, inhibiting the production of downstream thromboxanes and prostaglandins.

(Eicosanoid Metabolism Pathway, NCI Thesaurus/BIOCARTA)