CORTISONE

Pronunciation (US):

(GB):

IPA (US):

 Dictionary entry overview: What does cortisone mean? 

• CORTISONE (noun)
  The noun CORTISONE has 1 sense:

1. a corticosteroid hormone (trade name Cortone Acetate) normally produced by the adrenal cortex; is converted to hydrocortisone

  Familiarity information: CORTISONE used as a noun is very rare.

 Dictionary entry details 

• CORTISONE (noun)

Sense 1

Meaning:

A corticosteroid hormone (trade name Cortone Acetate) normally produced by the adrenal cortex; is converted to hydrocortisone

Classified under:

Nouns denoting substances

Synonyms:

cortisone; Cortone Acetate

Hypernyms ("cortisone" is a kind of...):

adrenal cortical steroid; corticoid; corticosteroid (a steroid hormone produced by the adrenal cortex or synthesized; administered as drugs they reduce swelling and decrease the body's immune response)

ketosteroid (a steroid containing a ketone group)

 Context examples 

Mutation of the gene is associated with cortisone reductase deficiency.

(HSD11B1 wt Allele, NCI Thesaurus)

Glycyrrhizinic acid in licorice root extract is hydrolyzed to glycyrrhetic acid (GA); GA inhibits 11 beta-hydroxysteroid dehydrogenase, resulting in inhibition of the conversion of cortisol to the inactive steroid cortisone and elevated cortisol levels.

(Licorice, NCI Thesaurus)

Cortisone acetate diffuses through the cell membrane and binds to nuclear glucocorticoid receptors.

(Cortisone Acetate, NCI Thesaurus)

Cortisone reduces swelling and can suppress immune responses.

(Cortisone, NCI Dictionary)

This protein is involved in cortisone metabolism.

(Corticosteroid 11-Beta-Dehydrogenase Isozyme 1, NCI Thesaurus)

The specificity of MR for aldosterone is provided by 11beta-HSD2 by the rapid conversion of cortisol to cortisone in renal cortical collecting duct cells.

(Aldosterone-Regulated Sodium Reabsorption Pathway, NCI Thesaurus/KEGG)

The A strain mouse has an albino coat (genotype a,b,c) and is susceptible to carcinogen-induced lung adenomas and cleft palate formation in response to cortisone.

(A/J Mouse, NCI Thesaurus)

In this mouse model, cleft palate formation can be induced by cortisone while alloxan treatment induces diabetes in a high percentage of CF-1 mice.

(CF-1 Mouse, NCI Thesaurus)

The acetate salt form of cortisone, a synthetic or semisynthetic analog of the naturally occurring cortisone hormone produced by the adrenal glands with anti-inflammatory and immunomodulating properties.

(Cortisone Acetate, NCI Thesaurus)