CONJUGATED

Pronunciation (US):

(GB):

IPA (US):

 Dictionary entry overview: What does conjugated mean? 

• CONJUGATED (adjective)
  The adjective CONJUGATED has 3 senses:

1. formed by the union of two compounds

2. joined together especially in a pair or pairs

3. of an organic compound; containing two or more double bonds each separated from the other by a single bond

  Familiarity information: CONJUGATED used as an adjective is uncommon.

 Dictionary entry details 

• CONJUGATED (adjective)

Sense 1

Meaning:

Formed by the union of two compounds

Synonyms:

conjugate; conjugated

Context example:

a conjugated protein

Similar:

bound (held with another element, substance or material in chemical or physical union)

Domain category:

chemical science; chemistry (the science of matter; the branch of the natural sciences dealing with the composition of substances and their properties and reactions)

Sense 2

Meaning:

Joined together especially in a pair or pairs

Synonyms:

conjugate; conjugated; coupled

Similar:

united (characterized by unity; being or joined into a single entity)

Sense 3

Meaning:

Of an organic compound; containing two or more double bonds each separated from the other by a single bond

Synonyms:

conjugate; conjugated

Similar:

bound (held with another element, substance or material in chemical or physical union)

Domain category:

chemical science; chemistry (the science of matter; the branch of the natural sciences dealing with the composition of substances and their properties and reactions)

 Context examples 

An immunotoxin consisting of a murine monoclonal antibody (MCA) conjugated to the toxin ricin.

(Murine MCA Ricin Conjugate, NCI Thesaurus)

An antibody-drug conjugate (ADC) containing an antibody directed against the scr-like kinase Fyn3 (SC-16), conjugated to the cytotoxic agent D6.5, with potential antineoplastic activity.

(Antibody-Drug Conjugate SC16LD6.5, NCI Thesaurus)

A cancer vaccine consisting of autologous ovarian cancer cell peptide antigens conjugated to the hapten 2,4-dinitrophenol (DNP) with potential immunostimulating and antineoplastic activities.

(Autologous Dinitrophenyl-Modified Ovarian Cancer Vaccine, NCI Thesaurus)

MUC2 protein is conjugated with KLH, an immunostimulant and a hapten carrier, to enhance immune recognition.

(MUC-2-KLH Vaccine, NCI Thesaurus)

A vaccine consisting of myeloma-specific immunoglobulin conjugated to keyhole limpet hemocyanin (KLH), an immune stimulant, with potential antineoplastic activity.

(Myeloma Ig Id-KLH Conjugate Vaccine, NCI Thesaurus)

Functioning in diverse regulatory activities, proteins conjugated to UBLs like Nedd8 typically are not targeted for proteasomal degradation.

(NAE Inhibitor MLN4924, NCI Thesaurus)

A fully human IgG1 monoclonal antibody directed against the cell surface glycoprotein mesothelin and conjugated to the maytansinoid DM4 with potential antineoplastic activity.

(Anti-mesothelin Antibody-Drug Conjugate BAY 94-9343, NCI Thesaurus)

A peptide vaccine containing the human tumor-associated antigen epithelial mucin (MUC1 antigen) conjugated with keyhole limpet hemocyanin (KLH) and combined with the nonspecific immunoadjuvant QS21, with potential antineoplastic activity.

(MUC1-KLH Vaccine/QS21, NCI Thesaurus)

A cancer vaccine composed of tumor-specific idiotype determinants derived from an individual's tumor cells which are conjugated to keyhole limpet hemocyanin, an immunostimulant carrier protein.

(Autologous Immunoglobulin Idiotype-KLH Conjugate Vaccine, NCI Thesaurus)

It may be conjugated with a radioactive element and used in radioimmunotherapy (RIT), a procedure that uses a tumor-specific monoclonal antibody to target radiation to cancer cells.

(Monoclonal Antibody m170, NCI Thesaurus)