COMPLEMENTARY DNA

Pronunciation (US):

(GB):

 Dictionary entry overview: What does complementary DNA mean? 

• COMPLEMENTARY DNA (noun)
  The noun COMPLEMENTARY DNA has 1 sense:

1. single-stranded DNA that is complementary to messenger RNA or DNA that has been synthesized from messenger RNA by reverse transcriptase

  Familiarity information: COMPLEMENTARY DNA used as a noun is very rare.

 Dictionary entry details 

• COMPLEMENTARY DNA (noun)

Sense 1

Meaning:

Single-stranded DNA that is complementary to messenger RNA or DNA that has been synthesized from messenger RNA by reverse transcriptase

Classified under:

Nouns denoting substances

Synonyms:

cDNA; complementary DNA

Hypernyms ("complementary DNA" is a kind of...):

deoxyribonucleic acid; desoxyribonucleic acid; DNA ((biochemistry) a long linear polymer found in the nucleus of a cell and formed from nucleotides and shaped like a double helix; associated with the transmission of genetic information)

Hyponyms (each of the following is a kind of "complementary DNA"):

provirus (cDNA copy of the RNA genome of a retrovirus; the genetic material of a virus as incorporated into and able to replicate with the genome of a host cell)

dscDNA (double-stranded cDNA)

 Context examples 

The product of this reaction is then applied to a nitrocellulose test strip containing complementary DNA probes.

(Line Probe Assay, NCI Thesaurus)

It may contain complete genomic sequences (GENOMIC LIBRARY) or complementary DNA sequences, the latter being formed from messenger RNA and lacking intron sequences.

(Gene Bank, NLM, Medical Subject Headings)

Specifically, they produced complementary DNA sequences (cDNA) for each protein, which are stretches of DNA with all the pieces not necessary for producing the protein removed.

(New studies may bring slug-made glues closer to use in medicine, Wikinews)

Base-Base Mismatch results from mutagenic factors that induce chemical modification of DNA bases so that pairing between specific bases on complementary DNA strands is eliminated causing mispairing.

(Base-Base Mismatch, NCI Thesaurus)

Expression vectors containing the complementary DNA (cDNA) of the cytokine granulocyte-macrophage colony-stimulating factor (GM-CSF) coated onto gold particles.

(GM-CSF cDNA/Gold Complex, NCI Thesaurus)

The labeled, denatured DNA fragments are applied to a DNA microarray where they can hybridize to their complementary DNA sequence.

(ChIP-On-Chip, NCI Thesaurus)

When introduced as the complementary DNA (cDNA) form into tumor cells by, for example, a genetically engineered adenovirus vector, the transfected IL-2 cDNA expresses IL-2 which may activate antitumoral natural killer cells and elicit an antitumoral cytotoxic T-cell response, resulting in an inhibition of tumor progression.

(Interleukin-2 Gene, NCI Thesaurus)

When introduced as the complementary DNA (cDNA) form into tumor cells by, for example, a genetically engineered adenovirus vector, the transfected IL-12 cDNA expresses IL-12 which activates antitumoral natural killer (NK) cells and CD8+ T-cells and stimulates the secretion of interferon-gamma (IFN-gamma), potentially inhibiting tumor cell metastasis.

(Interleukin-12 Gene, NCI Thesaurus)

They extracted ribonucleic acid (RNA) sequences from each sample and converted them into stable complementary DNA (cDNA), which was processed using a technique called real-time polymerase chain reaction (PCR), which amplifies the signal of genes activated by the multiplication of cDNA molecules.

(New method to classify brain tumour in children, SciDev.Net)