COLLAGENASE

Pronunciation (US):

(GB):

 Dictionary entry overview: What does collagenase mean? 

• COLLAGENASE (noun)
  The noun COLLAGENASE has 1 sense:

1. any enzyme that catalyzes the hydrolysis of collagen and gelatin

  Familiarity information: COLLAGENASE used as a noun is very rare.

 Dictionary entry details 

• COLLAGENASE (noun)

Sense 1

Meaning:

Any enzyme that catalyzes the hydrolysis of collagen and gelatin

Classified under:

Nouns denoting substances

Hypernyms ("collagenase" is a kind of...):

enzyme (any of several complex proteins that are produced by cells and act as catalysts in specific biochemical reactions)

 Context examples 

The collagenase gene, containing AP-1 sites, is also regulated by AP-1 components, including c-Jun.

(Angiotensin II Signaling Pathway, NCI Thesaurus/BIOCARTA)

Neutrophil collagenase (467 aa, ~53 kDa) is encoded by the human MMP8 gene.

(Neutrophil Collagenase, NCI Thesaurus)

In addition, this agent has exhibited inhibition of collagenase activity.

(Doxycycline, NCI Thesaurus)

This protein is involved in both extracellular matrix proteolysis and the activation of 72 kDa type IV collagenase.

(Matrix Metalloproteinase-14, NCI Thesaurus)

Collagenases are enzymes that degrade collagen fibers.

(Collagenase, NCI Thesaurus)

Collagenase 3 (471 aa, ~54 kDa) is encoded by the human MMP13 gene.

(Collagenase 3, NCI Thesaurus)

This allele, which encodes neutrophil collagenase protein, is involved in the regulation of matrix remodeling via the degradation of fibrillar collagens (types I, II and III).

(MMP8 wt Allele, NCI Thesaurus)

This allele, which encodes 72 kDa type IV collagenase protein, is involved in the breakdown of the extracellular matrix via the degradation of type IV collagen, the major structural component of basement membranes.

(MMP2 wt Allele, NCI Thesaurus)

This allele, which encodes collagenase 3 protein, is involved in collagen catabolism.

(MMP13 wt Allele, NCI Thesaurus)

This allele, which encodes interstitial collagenase protein, is involved in the breakdown of the extracellular matrix via the degradation of interstitial collagens (types I, II and III).

(MMP1 wt Allele, NCI Thesaurus)