CODON

Pronunciation (US):

(GB):

 Dictionary entry overview: What does codon mean? 

• CODON (noun)
  The noun CODON has 1 sense:

1. a specific sequence of three adjacent nucleotides on a strand of DNA or RNA that specifies the genetic code information for synthesizing a particular amino acid

  Familiarity information: CODON used as a noun is very rare.

 Dictionary entry details 

• CODON (noun)

Sense 1

Meaning:

A specific sequence of three adjacent nucleotides on a strand of DNA or RNA that specifies the genetic code information for synthesizing a particular amino acid

Classified under:

Nouns denoting substances

Hypernyms ("codon" is a kind of...):

sequence (serial arrangement in which things follow in logical order or a recurrent pattern)

 Context examples 

Also, by nonstop decay, mRNA surveillance depletes mRNAs that lack in-frame termination codons.

(mRNA Surveillance, NCI Thesaurus)

Mutation locations are notably at codons 12, 13, and 61.

(Mutated Ras Peptide, NCI Thesaurus)

K-RAS ASP-12 contains a mutation at codon 12 and may be used in cancer immunotherapy.

(K-RAS ASP-12 Mutant Protein, NCI Thesaurus)

By reappropriating naturally occurring stop codons, researchers have previously been able to incorporate synthetic non-standard amino acids, the building blocks of proteins, into protein structures in living cells.

(Expanding the Genetic Alphabet, NIH)

In eukaryotes, the non-stop decay mechanism recognizes and degrades mRNAs that lack a stop codon.

(Non-Stop Decay, NCI Thesaurus)

A sequence of nucleotides in that contains no termination codons and so can potentially translate as a polypeptide chain.

(Open Reading Frame, NCI Thesaurus)

The sodium salt of a phosphorothioate antisense oligonucleotide targeted to the initiation codon region of mRNA for the anti-apoptotic gene Bcl-2.

(Oblimersen sodium, NCI Thesaurus)

NMD is initiated during translation when hUpf proteins phosphorylated by SMG proteins cooperate with an exon-junction complex to identify mRNAs with premature stop codons and mark the transcript for rapid decay.

(Nonsense-Mediated Decay, NCI Thesaurus)

A missense non-synonymous SNP results in an amino acid change in the protein product due to a codon change, while a nonsense non-synonymous SNP results in a termination codon.

(Non-synonymous Coding SNP, NCI Thesaurus)

Mutations that add a premature stop codon to the gene are a factor in the occurrence of maturity-onset of diabetes, type 5.

(HNF1B wt Allele, NCI Thesaurus)