CHROMATIN

Pronunciation (US):

(GB):

 Dictionary entry overview: What does chromatin mean? 

• CHROMATIN (noun)
  The noun CHROMATIN has 1 sense:

1. the readily stainable substance of a cell nucleus consisting of DNA and RNA and various proteins; during mitotic division it condenses into chromosomes

  Familiarity information: CHROMATIN used as a noun is very rare.

 Dictionary entry details 

• CHROMATIN (noun)

Sense 1

Meaning:

The readily stainable substance of a cell nucleus consisting of DNA and RNA and various proteins; during mitotic division it condenses into chromosomes

Classified under:

Nouns denoting body parts

Synonyms:

chromatin; chromatin granule

Hypernyms ("chromatin" is a kind of...):

body substance (the substance of the body)

Hyponyms (each of the following is a kind of "chromatin"):

sex chromatin (chromatin found only in female cells)

Holonyms ("chromatin" is a part of...):

cell nucleus; karyon; nucleus (a part of the cell containing DNA and RNA and responsible for growth and reproduction)

chromosome (a threadlike strand of DNA in the cell nucleus that carries the genes in a linear order)

Derivation:

chromatinic ((of substance of a cell nucleus) readily colored by stains)

 Context examples 

It is characterized by an abundant pale cytoplasm, indented nuclei with inconspicuous nucleoli, and open chromatin.

(Monocytoid B-Lymphocyte, NCI Thesaurus)

It is about 12 to 20 micrometer in diameter, has a round to oval nucleus with fine, lightly dispersed chromatin and one to four nucleoli.

(Monoblast, NCI Thesaurus)

The Drosophila gene moira (mor) encodes a non-specific RNA polymerase II transcription factor involved in chromatin modeling, which is a component of the nucleosome remodeling complex.

(MOIRA Gene Product, NCI Thesaurus)

This allele, which encodes metastasis-associated protein MTA1, is involved in the regulation of gene transcription that may be the result of binding to the estrogen receptor or remodeling of chromatin.

(MTA1 wt Allele, NCI Thesaurus)

This allele, which encodes metastasis-associated protein MTA2, is involved in the modification of chromatin.

(MTA2 wt Allele, NCI Thesaurus)

A lymphoid cell of follicular center cell origin that has an irregularly shaped nucleus with clumped chromatin, absent nucleoli, and one or more clefts in the nuclear membrane.

(Murine Small Cleaved Cell, NCI Thesaurus)

Upon administration, mTOR1/2 Kinase inhibitor ME-344 downregulates the PIK3/AKT/mTOR pathway and results in chromatin condensation in the absence of caspase activation.

(mTOR1/2 Kinase Inhibitor ME-344, NCI Thesaurus)

While RCC1 helps RAN drive transport between the nucleus and cytoplasm during interphase, the localization of RCC1 on chromatin during mitosis localizes Ran-GTP near chromosomes, localizing microtubule formation in these regions.

(Mitotic Spindle Regulation Pathway, NCI Thesaurus/BIOCARTA)

This protein plays a role in transcriptional regulation mediated by chromatin remodeling.

(AT-Rich Interactive Domain-Containing Protein 1B, NCI Thesaurus)

DNA wraps around histones to form chromatin, which packages DNA in the nucleus.

(Scientists find promising drug combination against lethal childhood brain cancers, National Institutes of Health)