CHLORAMPHENICOL

Pronunciation (US):

(GB):

 Dictionary entry overview: What does chloramphenicol mean? 

• CHLORAMPHENICOL (noun)
  The noun CHLORAMPHENICOL has 1 sense:

1. an oral antibiotic (trade name Chloromycetin) used to treat serious infections (especially typhoid fever)

  Familiarity information: CHLORAMPHENICOL used as a noun is very rare.

 Dictionary entry details 

• CHLORAMPHENICOL (noun)

Sense 1

Meaning:

An oral antibiotic (trade name Chloromycetin) used to treat serious infections (especially typhoid fever)

Classified under:

Nouns denoting man-made objects

Synonyms:

chloramphenicol; Chloromycetin

Hypernyms ("chloramphenicol" is a kind of...):

antibiotic; antibiotic drug (a chemical substance derivable from a mold or bacterium that can kill microorganisms and cure bacterial infections)

 Context examples 

The sodium succinate salt form of chloramphenicol, a nitrobenzene derivate and broad-spectrum antibiotic with antibacterial activity.

(Chloramphenicol Sodium Succinate, NCI Thesaurus)

A disorder observed in a newborn who was exposed to chloramphenicol.

(Gray Baby Syndrome, NCI Thesaurus)

The presence of this enzyme confers chloramphenicol resistance to bacteria, which is used as a marker for selection in molecular techniques that utilize genetic transfection.

(Chloramphenicol O-acetyltransferase, NCI Thesaurus)

This product is not an inhibitor of peptidyltransferase, the enzyme responsible for natural chloramphenicol resistance in bacteria.

(CAT Gene, NCI Thesaurus)

Chloramphenicol diffuses through the bacterial cell wall and reversibly binds to the bacterial 50S ribosomal subunit.

(Chloramphenicol, NCI Thesaurus)

Moreover, the genomes of the high antibiotic use group contained genes for resistance to antibiotics typically not given to newborns, such as ciprofloxacin and chloramphenicol.

(Prolonged antibiotic treatment may alter preterm infants’ microbiome, National Institutes of Health)

Chloramphenicol sodium succinate reversibly binds to the 50S subunit of bacterial ribosomes, thereby interfering with peptidyl transferase activity in the elongation process of protein synthesis.

(Chloramphenicol Sodium Succinate, NCI Thesaurus)

This enzyme detoxifies the antibiotic chloramphenicol via acetylation to yield chloramphenicol 3-acetate.

(Chloramphenicol O-acetyltransferase, NCI Thesaurus)