CENTROSOME

Pronunciation (US):

(GB):

 Dictionary entry overview: What does centrosome mean? 

• CENTROSOME (noun)
  The noun CENTROSOME has 1 sense:

1. small region of cytoplasm adjacent to the nucleus; contains the centrioles and serves to organize the microtubules

  Familiarity information: CENTROSOME used as a noun is very rare.

 Dictionary entry details 

• CENTROSOME (noun)

Sense 1

Meaning:

Small region of cytoplasm adjacent to the nucleus; contains the centrioles and serves to organize the microtubules

Classified under:

Nouns denoting body parts

Synonyms:

central body; centrosome

Hypernyms ("centrosome" is a kind of...):

cytol; cytoplasm (the protoplasm of a cell excluding the nucleus; is full of proteins that control cell metabolism)

Derivation:

centrosomic (of or relating to a centrosome)

 Context examples 

This allele, which encodes pericentriolar material 1 protein, plays a role in the regulation of centrosome formation.

(PCM1 wt Allele, NCI Thesaurus)

Alternate splicing of this gene results in many isoforms that localize to the centrosome and the Golgi apparatus, and interact with numerous signaling proteins from multiple signal transduction pathways.

(A Kinase Anchor Protein 9, NCI Thesaurus/LocusLink)

This allele, which encodes serine/threonine-protein kinase LATS2 protein, is involved in centrosome duplication and the maintenance of mitotic fidelity.

(LATS2 wt Allele, NCI Thesaurus)

This gene is involved in centrosome formation.

(PCM1 Gene, NCI Thesaurus)

This allele, which encodes ninein protein, plays a role in the modulation of centrosome structure.

(NIN wt Allele, NCI Thesaurus)

This gene is involved in the localization of the centrosome.

(NIN Gene, NCI Thesaurus)

This protein is involved in the formation of the centrosome.

(Pericentriolar Material 1 Protein, NCI Thesaurus)

This allele, which encodes FGFR1 oncogene partner protein, plays a role in anchoring microtubules to the centrosome.

(FGFR1OP wt Allele, NCI Thesaurus)

Any substance that inhibits Aurora kinase, a serine/threonine kinase that is involved in mitotic spindle morphology, centrosome function, chromatid separation, and cytokinesis.

(Aurora Kinase Inhibitor, NCI Thesaurus)

This protein plays a role in both centrosome formation and endocytosis.

(CAP-Gly Domain-Containing Linker Protein 1, NCI Thesaurus)