CEFOTAXIME

Pronunciation (US):

(GB):

 Dictionary entry overview: What does cefotaxime mean? 

• CEFOTAXIME (noun)
  The noun CEFOTAXIME has 1 sense:

1. a parenteral cephalosporin (trade name Claforan) used for severe infections of the lungs or throat or ears or urinary tract

  Familiarity information: CEFOTAXIME used as a noun is very rare.

 Dictionary entry details 

• CEFOTAXIME (noun)

Sense 1

Meaning:

A parenteral cephalosporin (trade name Claforan) used for severe infections of the lungs or throat or ears or urinary tract

Classified under:

Nouns denoting man-made objects

Synonyms:

cefotaxime; Claforan

Hypernyms ("cefotaxime" is a kind of...):

cephalosporin; Mefoxin (one of several broad spectrum antibiotic substances obtained from fungi and related to penicillin (trade names Mefoxin); addition of side chains has produced semisynthetic antibiotics with greater antibacterial activity)

 Context examples 

Compared to the second and first generation cephalosporins, cefotaxime sodium is more active against gram-negative bacteria and less active against gram-positive bacteria.

(Cefotaxime Sodium, NCI Thesaurus)

Cefotaxime inhibits mucopeptide synthesis by binding to and inactivating penicillin binding proteins thereby interfering with the final transpeptidation step required for cross-linking of peptidoglycan units which are a component of bacterial cell walls.

(Cefotaxime, NCI Thesaurus)

This species is oxidase negative, fermentative, susceptible to ampicillin, amoxicillin-clavulanate, ceftazidime, ceftriaxone, cefotaxime, cefepime, ofloxacin, gentamicin, carbenicillin, and amikacin but resistant to cephalothin, penicillin G, and vancomycin.

(Ewingella americana, NCI Thesaurus)

Cefotaxime sodium binds to and inactivates penicillin-binding proteins (PBP) located on the inner membrane of the bacterial cell wall.

(Cefotaxime Sodium, NCI Thesaurus)

The sodium salt form of cefotaxime, a beta-lactam, third-generation cephalosporin antibiotic with bactericidal activity.

(Cefotaxime Sodium, NCI Thesaurus)