CDNA

Pronunciation (US):

(GB):

 Dictionary entry overview: What does cDNA mean? 

• CDNA (noun)
  The noun CDNA has 1 sense:

1. single-stranded DNA that is complementary to messenger RNA or DNA that has been synthesized from messenger RNA by reverse transcriptase

  Familiarity information: CDNA used as a noun is very rare.

 Dictionary entry details 

• CDNA (noun)

Sense 1

Meaning:

Single-stranded DNA that is complementary to messenger RNA or DNA that has been synthesized from messenger RNA by reverse transcriptase

Classified under:

Nouns denoting substances

Synonyms:

cDNA; complementary DNA

Hypernyms ("cDNA" is a kind of...):

deoxyribonucleic acid; desoxyribonucleic acid; DNA ((biochemistry) a long linear polymer found in the nucleus of a cell and formed from nucleotides and shaped like a double helix; associated with the transmission of genetic information)

Hyponyms (each of the following is a kind of "cDNA"):

provirus (cDNA copy of the RNA genome of a retrovirus; the genetic material of a virus as incorporated into and able to replicate with the genome of a host cell)

dscDNA (double-stranded cDNA)

 Context examples 

Any state accompanied by evidence of human immunodeficiency virus in the body (positive test for HIV genome, cDNA, proteins, antigens, or antibodies).

(HIV Infection, NCI Thesaurus/CDISC)

After the first four G proteins (Gs, Gt, Gi, and Go) were identified by biochemical purification, a large number of G proteins and their subunits were identified by cDNA cloning (2).

(Heterotrimeric G Protein, NCI Thesaurus)

Expression vectors containing the complementary DNA (cDNA) of the cytokine granulocyte-macrophage colony-stimulating factor (GM-CSF) coated onto gold particles.

(GM-CSF cDNA/Gold Complex, NCI Thesaurus)

Any bands unique to single samples are considered to be differentially expressed; they can be purified from the gel, and sequenced and used to clone the full-length cDNA.

(Differential Display, NCI Thesaurus)

The DNA sequence in the host cell is detected by hybridization with a biotin-labeled cDNA probe.

(In Situ Hybridization Staining Method, NCI Thesaurus)

They anticipate arraying (and sharing) cDNA libraries from additional species over time.

(Integrated Molecular Analysis of Genomes and their Expression Consortium, NCI Thesaurus)

PCR analysis of tumor cDNA and genomic DNA detected a PATZ1/UQCRH fusion transcript but it is out-of-frame and contains premature stop codons.

(PATZ1/UQCRH Fusion Gene, NCI Thesaurus)

The NQO1 *2 allele has a C609T substitution in the cDNA, which encodes NAD(P)H dehydrogenase [quinone] 1*2 protein that results in the amino acid change P187S.

(NQO1*2 Allele, NCI Thesaurus)

A murine retrovirus containing human PDGFB cDNA may be used to induce brain tumors in animal models of brain tumorigenesis.

(Murine Retrovirus Containing Human PDGFB cDNA, NCI Thesaurus)

The resulting cDNA library will be enriched for sequences expressed only in the tester cells. cDNA subtraction can also be done by PCR.

(cDNA Subtraction, NCI Thesaurus/OSP)