CASCADES

Pronunciation (US):

(GB):

IPA (US):

 Dictionary entry overview: What does Cascades mean? 

• CASCADES (noun)
  The noun CASCADES has 1 sense:

1. a mountain range in the northwestern United States extending through Washington and Oregon and northern California; a part of the Coast Range

  Familiarity information: CASCADES used as a noun is very rare.

 Dictionary entry details 

• CASCADES (noun)

Sense 1

Meaning:

A mountain range in the northwestern United States extending through Washington and Oregon and northern California; a part of the Coast Range

Classified under:

Nouns denoting natural objects (not man-made)

Synonyms:

Cascade Mountains; Cascade Range; Cascades

Instance hypernyms:

chain; chain of mountains; mountain chain; mountain range; range; range of mountains (a series of hills or mountains)

Meronyms (parts of "Cascades"):

Mount Saint Helens; Mount St. Helens; Mt. St. Helens (an active volcano in the Cascade Range in southwestern Washington; erupted violently in 1980 after 123 years of inactivity)

Adams; Mount Adams (a mountain peak in southwestern Washington in the Cascade Range (12,307 feet high))

Mount Rainier; Mount Tacoma; Mt. Rainier; Rainier (a mountain peak in central Washington; highest peak in the Cascade Range; (14,410 feet high))

Holonyms ("Cascades" is a part of...):

Northwest; northwestern United States (the northwestern region of the United States)

Coast Mountains; Coast Range (a string of mountain ranges along the Pacific coast of North America from southeastern Alaska to Lower California)

 Context examples 

This allele, which encodes COP9 signalosome complex subunit 1, is involved in the modulation of both G-protein coupled receptor and mitogen-activated kinase signaling cascades.

(GPS1 wt Allele, NCI Thesaurus)

The activity of JAK2 mediates many of the downstream responses to growth hormone through phosphorylation of STAT transcription factors, MAP kinases, other kinase cascades and molecules involved in metabolism like IRS-1.

(Growth Hormone Signaling Pathway, NCI Thesaurus/BIOCARTA)

Genotoxic stresses frequently activate signal transduction pathways that originate in the cell membrane or cytoplasm, triggering similar phosphorylation cascades to those induced by the activation of cell-surface receptors.

(Genotoxic Stress, NCI Thesaurus)

Activation of Map kinase cascades leads to Erk1/Erk2 dependent p47phox phosphorylation as well as activation of the Elk-1 transcription factor and chemokine gene expression.

(Formyl Peptide Receptor 1 Signaling Pathway, NCI Thesaurus/BIOCARTA)

After analyzing dozens of samples, the team identified a blue-colored clay from the Oregon Cascades that proved to be highly antibacterial.

(Scientists discover how blue and green clays kill bacteria, NSF)

Map kinase cascades mediate Hsp27 phosphorylation.

(HSP27 Regulation Pathway, NCI Thesaurus/BIOCARTA)

IRAK4 may act as an IRAK1 kinase, triggering phosphorylation cascades.

(Interleukin-1 Receptor-Associated Kinase 4, NCI Thesaurus)

As with other MAPK cascades, the membrane-proximal component is a MAPKKK, typically a MEKK or a mixed lineage kinase (MLK).

(p38 MAPK Signaling Pathway BioCarta, NCI Thesaurus/BIOCARTA)

Hydrolytic activity initiates signaling cascades in the cell.

(Phospholipase, NCI Thesaurus)

Neurotrophin/Trk signaling is regulated by connecting a variety of intracellular signaling cascades, which include MAPK pathway, PI-3 kinase pathway, and PLC pathway, transmitting positive signals like enhanced survival and growth.

(Neurotrophin Signaling Pathway, NCI Thesaurus/KEGG)