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CARDIAC GLYCOSIDE
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Dictionary entry overview: What does cardiac glycoside mean?
• CARDIAC GLYCOSIDE (noun)
The noun CARDIAC GLYCOSIDE has 1 sense:
1. obtained from a number of plants and used to stimulate the heart in cases of heart failure
Familiarity information: CARDIAC GLYCOSIDE used as a noun is very rare.
Dictionary entry details
Sense 1
Meaning:
Obtained from a number of plants and used to stimulate the heart in cases of heart failure
Classified under:
Nouns denoting substances
Synonyms:
cardiac glucoside; cardiac glycoside
Hypernyms ("cardiac glycoside" is a kind of...):
steroid (any of several fat-soluble organic compounds having as a basis 17 carbon atoms in four rings; many have important physiological effects)
Hyponyms (each of the following is a kind of "cardiac glycoside"):
digitalin; digitalis; digitalis glycoside (a powerful cardiac stimulant obtained from foxglove)
Context examples
A lipid soluble cardiac glycoside with potential antineoplastic activity.
(Oleandrin, NCI Thesaurus)
A traditional Chinese medicine (TCM) containing a water soluble Bufo toad skin extract that includes the cardiac glycosides bufalin, cinobufagin and resibufogenin with potential antineoplastic and antiangiogenic activities.
(HuaChanSu, NCI Thesaurus)
It is a type of cardiac glycoside.
(Digitalis, NCI Dictionary)
A lipid soluble cardiac glycoside that inhibits the plasma membrane sodium potassium ATPase, leading to increased intracellular sodium and calcium levels and decreased intracellular potassium levels.
(Digitoxin, NCI Thesaurus)
A cardiac glycoside.
(Digoxin, NCI Thesaurus)
As cancer cells with relatively higher expression of the alpha3 subunit and with limited expression of the alpha1 subunit are more sensitive to oleandrin, one may predict the tumor response to treatment with lipid-soluble cardiac glycosides such as oleandrin based on the tumors Na/K-ATPase pump protein subunit expression.
(Oleandrin, NCI Thesaurus)
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