BLOOD-BRAIN BARRIER

Pronunciation (US):

(GB):

IPA (US):

 Dictionary entry overview: What does blood-brain barrier mean? 

• BLOOD-BRAIN BARRIER (noun)
  The noun BLOOD-BRAIN BARRIER has 1 sense:

1. a mechanism that creates a barrier between brain tissues and circulating blood; serves to protect the central nervous system

  Familiarity information: BLOOD-BRAIN BARRIER used as a noun is very rare.

 Dictionary entry details 

• BLOOD-BRAIN BARRIER (noun)

Sense 1

Meaning:

A mechanism that creates a barrier between brain tissues and circulating blood; serves to protect the central nervous system

Classified under:

Nouns denoting natural objects (not man-made)

Context example:

the brain was protected from the large molecules of the virus by the blood-brain barrier

Hypernyms ("blood-brain barrier" is a kind of...):

barrier (anything serving to maintain separation by obstructing vision or access)

 Context examples 

Gadopentetate dimeglumine may provide contrast enhancement during magnetic resonance imaging (MRI) of intracranial lesions with abnormal vascularity or of abnormalities in the blood-brain barrier (BBB).

(Gadopentetate dimeglumine, NCI Thesaurus)

Gadoversetamide does not cross the intact blood-brain barrier.

(Gadoversetamide, NCI Thesaurus)

In addition, hydroxyzine hydrochloride crosses the blood-brain barrier and acts on the histamine H1-receptors in the central nervous system.

(Hydroxyzine Hydrochloride, NCI Thesaurus)

This agent is lipophilic and crosses the blood-brain barrier.

(Fotemustine, NCI Thesaurus)

This agent is metabolically stable, accumulates in the normal bone marrow and the liver, and does not cross the blood-brain barrier.

(Fluorothymidine F-18, NCI Thesaurus)

They focused on agents that could both kill DIPG cells and cross the brain’s protective blood-brain barrier, a necessity for a drug to be effective against DIPG in patients.

(Scientists find promising drug combination against lethal childhood brain cancers, National Institutes of Health)

Lipid-soluble etoprine is capable of crossing the blood-brain barrier.

(Etoprine, NCI Thesaurus)

Fluorine F 18 fluorodopa is able to cross the blood-brain barrier and is taken up by brain tumor cells.

(Fluorine F 18 Fluorodopa, NCI Thesaurus)

In addition, hydroxyzine pamoate crosses the blood-brain barrier and acts on the histamine H1-receptors in the central nervous system.

(Hydroxyzine Pamoate, NCI Thesaurus)

Lipid-soluble metoprine is capable of crossing the blood-brain barrier.

(Metoprine, NCI Thesaurus)