ATTENUATED

Pronunciation (US):

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IPA (US):

 Dictionary entry overview: What does attenuated mean? 

• ATTENUATED (adjective)
  The adjective ATTENUATED has 2 senses:

1. of an electrical signal; reduced in amplitude with little or no distortion

2. reduced in strength

  Familiarity information: ATTENUATED used as an adjective is rare.

 Dictionary entry details 

• ATTENUATED (adjective)

Sense 1

Meaning:

Of an electrical signal; reduced in amplitude with little or no distortion

Similar:

decreased; reduced (made less in size or amount or degree)

Domain category:

electronics (the branch of physics that deals with the emission and effects of electrons and with the use of electronic devices)

Sense 2

Meaning:

Reduced in strength

Synonyms:

attenuate; attenuated; faded; weakened

Context example:

the faded tones of an old recording

Similar:

decreased; reduced (made less in size or amount or degree)

 Context examples 

Originally developed for the eradication of smallpox, MVA is a highly attenuated and replication-defective strain incapable of virion assembly and exerts potent immunostimulatory activity against antigens.

(MVA-MUC1-IL2 Vaccine, NCI Thesaurus)

A trivalent vaccine containing live attenuated viruses that can cause measles, mumps and rubella.

(Measles/Mumps/Rubella Vaccine, NCI Thesaurus)

An attenuated form of Mycobacterium bovis that is used to generate the Bacillus Calmette-Guerin vaccine.

(Mycobacterium bovis BCG, NCI Thesaurus)

An attenuated strain of Mycobacterium w, a non-pathogenic, rapidly growing, atypical mycobacterium, with non-specific immunopotentiating properties.

(Mycobacterium w, NCI Thesaurus)

A gene therapy agent containing an attenuated, replication-competent, genetically engineered mutant form of the Herpes simplex virus 1 (HSV-1) strain KOS with potential antineoplastic activity.

(Oncolytic HSV-1 rRp450, NCI Thesaurus)

A cancer vaccine consisting of an attenuated recombinant vaccinia virus expressing the melanoma-associated antigen MART-1.

(MART-1 Vaccinia Vaccine, NCI Thesaurus)

The administration of live or attenuated influenza virus for the prophylaxis of influenza.

(Influenza Vaccination, NCI Thesaurus)

Upon subcutaneous administration, live attenuated measles virus vaccine may activate the immune system to mount a cytotoxic T-lymphocyte (CTL) response against measles-positive tumor cells.

(Live Attenuated Measles Virus Vaccine, NCI Thesaurus)

A recombinant Listeria-based cancer vaccine containing a live-attenuated strain of the facultative intracellular bacterium Listeria monocytogenes (Lm) expressing human mesothelin with potential immunostimulatory and antineoplastic activities.

(Live-Attenuated Listeria Encoding Human Mesothelin Vaccine CRS-207, NCI Thesaurus)

A vaccine that contains live attenuated influenza virus (LAIV) particles.

(Live Attenuated Influenza Vaccine, NCI Thesaurus)