ATAXIA

Pronunciation (US):

(GB):

IPA (US):

 Dictionary entry overview: What does ataxia mean? 

• ATAXIA (noun)
  The noun ATAXIA has 1 sense:

1. inability to coordinate voluntary muscle movements; unsteady movements and staggering gait

  Familiarity information: ATAXIA used as a noun is very rare.

 Dictionary entry details 

• ATAXIA (noun)

Sense 1

Meaning:

Inability to coordinate voluntary muscle movements; unsteady movements and staggering gait

Classified under:

Nouns denoting stable states of affairs

Synonyms:

ataxia; ataxy; dyssynergia; motor ataxia

Hypernyms ("ataxia" is a kind of...):

nervous disorder; neurological disease; neurological disorder (a disorder of the nervous system)

Hyponyms (each of the following is a kind of "ataxia"):

Friedreich's ataxia; herediatry spinal ataxia (sclerosis of the posterior and lateral columns of the spinal cord; characterized by muscular weakness and abnormal gait; occurs in children)

hereditary cerebellar ataxia (nervous disorder of late childhood and early adulthood; characterized by ataxic gait and hesitating or explosive speech and nystagmus)

Holonyms ("ataxia" is a part of...):

spinocerebellar disorder (any of several congenital disorders marked by degeneration of the cerebellum and spinal cord resulting in spasticity and ataxia)

Derivation:

atactic; ataxic (lacking motor coordination; marked or caused by ataxia)

 Context examples 

It may be associated with muscle weakness, heart block, hearing loss, ataxia and short stature.

(Kearns-Sayre Syndrome, NCI Thesaurus)

Signs and symptoms include truncal ataxia, disturbed gait, lethargy, headache, and vomiting.

(Medulloblastoma, NCI Thesaurus)

Signs and symptoms include psychomotor retardation, ataxia, recurrent fevers, skin rash, hepatosplenomegaly, and lymphadenopathy.

(Mevalonate Kinase Deficiency, NCI Thesaurus)

Signs and symptoms include retinitis pigmentosa which may lead to blindness, hearing problems and deafness, hypotonia, ataxia, nystagmus, facial deformities, and mental and growth retardation.

(Infantile Refsum Disease, NCI Thesaurus)

Ataxia telangiectasia is a disease that is resultant from mutations in the ATM gene, which is a cell cycle checkpoint gene.

(Genomic Instability, NCI Thesaurus)

Specific symptoms include: • Difficulty walking • Muscle weakness • Speech problems • Involuntary eye movements • Scoliosis (curving of the spine to one side) • Heart palpitations, from the heart disease which can happen along with Friedreich's ataxia

(Friedreich's Ataxia, NIH: National Institute of Neurological Disorders and Stroke)

Mutations of the gene are implicated in a rare disorder called spinocerebellar ataxia 2 that causes loss of balance and coordination.

(Glaucoma-related genes revealed, NIH)

This gene is involved in the regulation of gene expression and plays a role in the development of hepatocellular, lung and thyroid carcinomas, plasma cell myeloma, medulloblastoma, Cowden's syndrome and spinocerebellar ataxia.

(MIR19A Gene, NCI Thesaurus)

This allele, which encodes MIR19A RNA, plays a role in lung, liver, thyroid cancers, medulloblastoma, multiple myeloma, Cowden's syndrome and spinocerebellar ataxia.

(MIR19A wt Allele, NCI Thesaurus)

Signs and symptoms include seizures, delayed growth, behavioral changes, ataxia, lethargy, and coma.

(Ornithine Carbamoyltransferase Deficiency Disease, NCI Thesaurus)