ASPARAGINE

Pronunciation (US):

(GB):

 Dictionary entry overview: What does asparagine mean? 

• ASPARAGINE (noun)
  The noun ASPARAGINE has 1 sense:

1. a crystalline amino acid found in proteins and in many plants (e.g., asparagus)

  Familiarity information: ASPARAGINE used as a noun is very rare.

 Dictionary entry details 

• ASPARAGINE (noun)

Sense 1

Meaning:

A crystalline amino acid found in proteins and in many plants (e.g., asparagus)

Classified under:

Nouns denoting substances

Hypernyms ("asparagine" is a kind of...):

amino acid; aminoalkanoic acid (organic compounds containing an amino group and a carboxylic acid group)

 Context examples 

Due to low asparagine synthetase activity in tumor cells, de novo synthesis of asparagine is suppressed within tumor cells.

(Erythrocyte-encapsulated L-asparaginase Suspension, NCI Thesaurus)

Most of the proteins synthesized in the ER are cotranslationally modified with N (asparagine)-linked glycans by addition of triglycosylated, branched oligosaccharides at asparagines residues.

(Endoplasmic Reticulum Degradation Pathway, NCI Thesaurus/BIOCARTA)

This protein plays a role in the addition of high-mannose oligosaccharides to asparagine residues.

(Dolichyl-Diphosphooligosaccharide--Protein Glycosyltransferase Subunit DAD1, NCI Thesaurus)

It breaks down the amino acid asparagine and may block the growth of tumor cells that need asparagine to grow.

(Asparaginase, NCI Dictionary)

A synthetic form of the ras protein containing a point mutation at position 13 (glycine to asparagine).

(K-RAS ASP-13 Mutant Protein, NCI Thesaurus)

It contains malachite green, glycerol, asparagine, coagulated eggs, and mineral salts.

(Lowenstein-Jensen Medium, NCI Thesaurus)

Asparaginase hydrolyzes L-asparagine to L-aspartic acid and ammonia, thereby depleting these cells of asparagine and blocking protein synthesis and tumor cell proliferation, especially in the G1 phase of the cell cycle.

(Pegaspargase, NCI Thesaurus)

Asparagine is critical to protein synthesis in cancer cells, which cannot synthesize this amino acid due to the absence of the enzyme asparagine synthase.

(Pegylated Recombinant L-asparaginase Erwinia chrysanthemi, NCI Thesaurus)

Oncaspar-IV is an enzyme that breaks down the amino acid asparagine and may block the growth of tumor cells that need asparagine to grow.

(Oncaspar-IV, NCI Dictionary)

A growth medium that is especially used for the cultivation of mycobacterium consisting of LJ Medium without the asparagine.

(Ogawa Growth Medium, NCI Thesaurus)