ANTINEOPLASTIC

Pronunciation (US):

(GB):

 Dictionary entry overview: What does antineoplastic mean? 

• ANTINEOPLASTIC (noun)
  The noun ANTINEOPLASTIC has 1 sense:

1. any of several drugs that control or kill neoplastic cells; used in chemotherapy to kill cancer cells; all have unpleasant side effects that may include nausea and vomiting and hair loss and suppression of bone marrow function

  Familiarity information: ANTINEOPLASTIC used as a noun is very rare.

• ANTINEOPLASTIC (adjective)
  The adjective ANTINEOPLASTIC has 1 sense:

1. used in the treatment of cancer

  Familiarity information: ANTINEOPLASTIC used as an adjective is very rare.

 Dictionary entry details 

• ANTINEOPLASTIC (noun)

Sense 1

Meaning:

Any of several drugs that control or kill neoplastic cells; used in chemotherapy to kill cancer cells; all have unpleasant side effects that may include nausea and vomiting and hair loss and suppression of bone marrow function

Classified under:

Nouns denoting man-made objects

Synonyms:

antineoplastic; antineoplastic drug; cancer drug

Hypernyms ("antineoplastic" is a kind of...):

cytotoxic drug (any drug that has a toxic effect on cells; commonly used in chemotherapy to inhibit the proliferation of cancerous cells)

Hyponyms (each of the following is a kind of "antineoplastic"):

alkylating agent (an antineoplastic drug used to treat some forms of cancer)

antimetabolite (an antineoplastic drug that inhibits the utilization of a metabolite)

antineoplastic antibiotic (an antibiotic drug used as an antineoplastic in chemotherapy)

asparaginase; Elspar (antineoplastic drug (trade name Elspar) sometimes used to treat lymphoblastic leukemia)

floxuridine (antineoplastic drug used to treat some cancers; can cause loss of hair)

lomustine (an antineoplastic drug often used to treat brain tumors or Hodgkin's disease)

Alkeran; melphalan (antineoplastic drug (trade name Alkeran) used to treat multiple myeloma and some other malignancies)

periwinkle plant derivative (an antineoplastic drug used to treat some forms of cancer)

procarbazine (an antineoplastic drug used to treat Hodgkin's disease)

thioguanine (an antineoplastic drug used to treat acute leukemias)

thiotepa (an antineoplastic drug used to treat certain malignancies)

Derivation:

antineoplastic (used in the treatment of cancer)

• ANTINEOPLASTIC (adjective)

Sense 1

Meaning:

Used in the treatment of cancer

Classified under:

Relational adjectives (pertainyms)

Synonyms:

anticancer; antineoplastic; antitumor; antitumour

Context example:

an antineoplastic effect

Pertainym:

neoplasm (an abnormal new mass of tissue that serves no purpose)

Derivation:

antineoplastic (any of several drugs that control or kill neoplastic cells; used in chemotherapy to kill cancer cells; all have unpleasant side effects that may include nausea and vomiting and hair loss and suppression of bone marrow function)

 Context examples 

An orally available small molecule mitogen-activated protein kinase kinase (MAP2K, MAPK/ERK kinase, or MEK) inhibitor, with potential antineoplastic activity.

(MEK Inhibitor WX-554, NCI Thesaurus)

A synthetic, fungal metabolite analogue inhibitor of mitogen-activated protein kinase kinase 1 (MEK-1) and mitogen-activated protein kinase kinase kinase 1 (MEKK-1) with potential antipsoriatic and antineoplastic activities.

(MEK-1/MEKK-1 Inhibitor E6201, NCI Thesaurus)

An orally available dual inhibitor of mitogen-activated protein kinase kinase (MEK) and Aurora kinases, with potential antineoplastic activity.

(MEK/Aurora Kinase Inhibitor BI 847325, NCI Thesaurus)

An orally available inhibitor of maternal embryonic leucine zipper kinase (MELK) with potential antineoplastic activity.

(MELK Inhibitor OTS167, NCI Thesaurus)

An orally bioavailable small-molecule inhibitor of MEK1 and MEK2 (MEK1/2) with potential antineoplastic activity.

(MEK Inhibitor TAK-733, NCI Thesaurus)

An orally active, selective MEK inhibitor with potential antineoplastic activity.

(MEK Inhibitor AZD8330, NCI Thesaurus)

A replication-defective, E1- and E2b-deleted oncolytic adenoviral serotype 5 (Ad5) encoding an epitope of human carcinoembryonic antigen (CEA) with potential antineoplastic activity.

(Adenoviral Vector Ad5-CEA(6D) Vaccine, NCI Thesaurus)

A replication-defective, recombinant adenoviral serotype 5 (Ad5) encoding human guanylyl cyclase C (hGCC) and the synthetic Pan DR epitope (PADRE), with potential antineoplastic and immunomodulating activities.

(Adenovirus 5-Human Guanylyl Cyclase C-PADRE Vaccine, NCI Thesaurus)

An amide analogue of Trichostatin A studied for potential antineoplastic activity.

(A-65, NCI Thesaurus)

A demethoxy derivative of doxorubicin with antineoplastic activity.

(Medorubicin, NCI Thesaurus)