ANGIOTENSIN I

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 Dictionary entry overview: What does angiotensin I mean? 

• ANGIOTENSIN I (noun)
  The noun ANGIOTENSIN I has 1 sense:

1. a physiologically inactive form of angiotensin that is the precursor to angiotensin II

  Familiarity information: ANGIOTENSIN I used as a noun is very rare.

 Dictionary entry details 

• ANGIOTENSIN I (noun)

Sense 1

Meaning:

A physiologically inactive form of angiotensin that is the precursor to angiotensin II

Classified under:

Nouns denoting man-made objects

Hypernyms ("angiotensin I" is a kind of...):

angiotensin; angiotonin; Hypertensin (any of several vasoconstrictor substances (trade name Hypertensin) that cause narrowing of blood vessels)

 Context examples 

Irbesartan selectively and competitively blocks the binding of angiotensin II to the angiotensin I receptor.

(Irbesartan, NCI Thesaurus)

Libenzapril competitively binds to and inhibits ACE, thereby blocking the conversion of angiotensin I to angiotensin II.

(Libenzapril, NCI Thesaurus)

Imidaprilat competitively binds to and inhibits ACE, thereby blocking the conversion of angiotensin I to angiotensin II.

(Imidapril, NCI Thesaurus)

Any substance that inhibits angiotensin-converting enzyme (ACE), an enzyme that catalyzes the conversion of angiotensin I to angiotensin II.

(ACE inhibitor, NCI Thesaurus)

Enalaprilat prevents the conversion of angiotensin I into angiotensin II by inhibiting ACE, thereby leading to decreased vasopressor activity and resulting in vasodilation.

(Enalaprilat, NCI Thesaurus)

Lisinopril, a synthetic peptide derivative, competitively binds to and inhibits ACE, thereby blocking the conversion of angiotensin I to angiotensin II.

(Lisinopril Anhydrous, NCI Thesaurus)

Losartan potassium selectively and competitively blocks the binding of angiotensin II to the angiotensin I (AT1) receptor.

(Losartan, NCI Thesaurus)

Upon hydrolysis, the free SH metabolite of pivopril competitively binds to and inhibits ACE, thereby blocking the conversion of angiotensin I to angiotensin II.

(Pivopril, NCI Thesaurus)

Perindoprilat inhibits ACE and, thus, the conversion of angiotensin I to angiotensin II; consequently, angiotensin II-mediated vasoconstriction and angiotensin II-stimulated aldosterone secretion from the adrenal cortex are inhibited and diuresis and natriuresis ensue.

(Perindoprilat, NCI Thesaurus)

As a prodrug, pentopril is hydrolyzed into its active form pentoprilat, which competitively inhibits ACE, thereby blocking the conversion of angiotensin I to angiotensin II.

(Pentopril, NCI Thesaurus)