AMPLIFICATION

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 Dictionary entry overview: What does amplification mean? 

• AMPLIFICATION (noun)
  The noun AMPLIFICATION has 3 senses:

1. addition of extra material or illustration or clarifying detail

2. the amount of increase in signal power or voltage or current expressed as the ratio of output to input

3. (electronics) the act of increasing voltage or power or current

  Familiarity information: AMPLIFICATION used as a noun is uncommon.

 Dictionary entry details 

• AMPLIFICATION (noun)

Sense 1

Meaning:

Addition of extra material or illustration or clarifying detail

Classified under:

Nouns denoting acts or actions

Synonyms:

amplification; elaboration

Context example:

an elaboration of the sketch followed

Hypernyms ("amplification" is a kind of...):

expanding upon; expansion (adding information or detail)

Sense 2

Meaning:

The amount of increase in signal power or voltage or current expressed as the ratio of output to input

Classified under:

Nouns denoting attributes of people and objects

Synonyms:

amplification; gain

Hypernyms ("amplification" is a kind of...):

increase; increment (the amount by which something increases)

Hyponyms (each of the following is a kind of "amplification"):

loop gain ((telecommunication) the gain of a feedback amplifier or system as a function of how much output is fed back to the input)

Sense 3

Meaning:

(electronics) the act of increasing voltage or power or current

Classified under:

Nouns denoting acts or actions

Hypernyms ("amplification" is a kind of...):

increase; step-up (the act of increasing something)

Domain category:

electricity (a physical phenomenon associated with stationary or moving electrons and protons)

 Context examples 

A gene duplication abnormality may occur by gene amplification, random breakage and reunion, retrotransposition or unequal crossing-over at meiosis.

(Gene Duplication Abnormality, NCI Thesaurus)

It represents approximately 50% of diffuse large B-cell lymphomas, and is characterized by the expression of CD10, BCL-6, A-myb, and LMO2 genes, BCL-2 translocation, and c-REL amplification.

(Germinal Center B-Cell-Like Diffuse Large B-Cell Lymphoma, NCI Thesaurus)

In primary GBM, disruption of the p53 pathway often occurs through loss of ARF, or less frequently through amplification of MDM2.

(Glioblastoma Multiforme Pathway, NCI Thesaurus/KEGG)

Polymerase chain reaction (PCR), can be considered a type of man-made gene amplification process.

(Gene Amplification Technique, NCI Thesaurus)

Typically, the use of hybridization techniques to detect amplification or deletion of specific DNA sequences.

(Gene Amplification or Deletion Detection, NCI Thesaurus)

Amplification of a trinucleotide repeat (CGG) within the gene is associated with fragile X syndrome.

(FMR1 wt Allele, NCI Thesaurus)

Cdc25 then activates Cdc2, establishing a feedback amplification loop that efficiently drives the cell into mitosis.

(G2/M Checkpoint Pathway, NCI Thesaurus/BIOCARTA)

Gene amplification is common in cancer cells, and some amplified genes may cause cancer cells to grow or become resistant to anticancer drugs.

(Gene amplification, NCI Dictionary)

Recently, amplification of the MITF gene was demonstrated in 10% of primary melanomas and 20% of metastatic melanomas, suggesting that MITF is a melanoma oncogene.

(Melanoma Pathway, NCI Thesaurus/KEGG)

The bisulfite-treated sample is subjected to another round of amplification and subsequently analyzed by shotgun sequencing.

(MethylC-Seq, NCI Thesaurus)